Protein Alignment Ist1 and XB5993342

DIOPT Version :10

• Sequence 1: NP_648058.1
• Gene: Ist1 / 38750
• FlyBaseID: FBgn0035715
• Length: 417
• Species: Drosophila melanogaster
• Sequence 2: NP_001135497.1
• Gene: XB5993342 / 100216037
• XenbaseID: XB-GENE-5993343
• Length: 342
• Species: Xenopus tropicalis
• Alignment Length: 425
• Identity: 172/425 - (40%)
• Similarity: 221/425 - (52%)
• Gaps: 93/425 - (21%)

  Fly     1 MFSSGPNYNKLKTNLRLALNRLKLLEKKKAELTQKSRKEIADYLATGKTERARIRVEHIIREDYL 65
            |..||....:|:.|||||:||||||||||.|:..|:||||||||:..|.||||||||||||||||
 Frog     1 MLGSGFKAERLRVNLRLAINRLKLLEKKKTEMALKARKEIADYLSCRKDERARIRVEHIIREDYL 65

  Fly    66 VEAMEMVEMYCDLLLARFGLITQMKELDTGIAEPVASLVWVCPRLQSDIAELKIISDIFVTKYGP 130
            |||||::|:||||||||||||..|:|||.|:||.|::|:|..|||||:::||||::.....||..
 Frog    66 VEAMEILELYCDLLLARFGLIQSMRELDPGLAEAVSTLIWAAPRLQSEVSELKIVASQLCHKYSK 130

  Fly   131 QFAEQSRT-ATGEHYVSEKLMHKLTLQAPPKLLVENYLIAIAKNYNIEYEPDPQVMQED---QPQ 191
            ::....|| ..|.  ||:|||:||...||||:|||.|||.|||||.:.||||..:|.|.   ...
 Frog   131 EYGNLCRTNQIGT--VSDKLMNKLGTAAPPKILVEKYLIEIAKNYKVPYEPDAVIMGEAPTFSEV 193

  Fly   192 QPHLIDLSDRNNLSG---GGGAGGGGAAPPQMGFIGYPAMPALPDMPMPPSAKPFNYPPFGGGGG 253
            .|.:|...:.:...|   |||.|||.....|:             .|.|...|.|..|
 Frog   194 DPSIIGFVNDDKKGGPGNGGGFGGGDFRINQV-------------YPNPNDPKSFPDP------- 238

  Fly   254 GGGGGAPAGAYALPHPVQAPPPFAYNIP--PNQPPTHAVLPAKCAEEKDLNTNFIDREANNTDGS 316
                  ..|.|. |.....|||....||  |:.||:..:          :|....|..|:....|
 Frog   239 ------SVGIYE-PCAFLQPPPRGKMIPHVPDIPPSSNM----------MNNKGGDSGASPAMNS 286

  Fly   317 GSPDENILRPKPENDPPPRYTSINPVNLQNANKPKPQPRSKLPPGNPTLPSAPPALDFPSLPNVP 381
            |. .||:         |.:|.::              |..||    |::||:|.....||.|
 Frog   287 GQ-GENV---------PGKYNNL--------------PLPKL----PSVPSSPAHGSPPSDP--- 320

  Fly   382 NDLPDIPGAGAEKKNDEDEIDFDDLSRRFENLKKR 416
                          :..::|||:|||:|.:||||:
 Frog   321 --------------SPYEDIDFEDLSKRLDNLKKK 341

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ist1	NP_648058.1	Ist1	12..177	CDD:460910	106/165 (64%)
		PTZ00441	<273..>400	CDD:240420	27/128 (21%)
XB5993342	NP_001135497.1	Ist1	12..176	CDD:460910	106/165 (64%)
		PHA03247	<229..322	CDD:223021	34/161 (21%)