DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8549 and sbds-1

DIOPT Version :9

Sequence 1:	NP_001261482.1	Gene:	CG8549 / 38749	FlyBaseID:	FBgn0035714	Length:	252	Species:	Drosophila melanogaster
Sequence 2:	NP_497226.2	Gene:	sbds-1 / 175218	WormBaseID:	WBGene00021063	Length:	253	Species:	Caenorhabditis elegans

Alignment Length:	253	Identity:	146/253 - (57%)
Similarity:	190/253 - (75%)	Gaps:	8/253 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSK-IFTPTNQIRLTNVAIVRLKKGGKRFEIACYKNKVLSWRSNSEKDIDEVLQTHTVFTNVSKG 64
            ||| |.|||||..|||||:||:||.|||||||||||||::||:.|||||||||||||||:|||||
Worm     1 MSKNIKTPTNQKVLTNVAVVRMKKTGKRFEIACYKNKVVNWRNKSEKDIDEVLQTHTVFSNVSKG 65

  Fly    65 QAAKKDELQKAFNKTDETEICKEILSKGELQVSEKERQSCLDTQLNSIVNSVAALCVNPETRRPY 129
            |.:||:||..||...|:.||||.||.||:|||||||||:..|..|..:...:|::.|||||:||.
Worm    66 QLSKKEELIAAFGIEDQLEICKIILDKGDLQVSEKERQAASDQSLKEVSQLIASMVVNPETKRPV 130

  Fly   130 PASIIEKSLKDAHFSVKMNRNTKQNTLEAIKILKDHMPIERSRMKLRVSFAGKEGGG---KLKES 191
            |.|:|:|:|::.|||:|.||::||..|:||..|::.:.|||::||:||:...||...   |||
Worm   131 PPSVIDKALQEMHFSLKPNRSSKQQALDAIPKLRETLKIERAKMKIRVAIPTKEAKSVHTKLK-- 193

  Fly   192 VVKLANAVEHEEWDEATLHLTLLIDPGQYRVIDELVRNETKGKGLLELLELKEVVESE 249
              .|.:.||.::|.:.:|.:..||:||.:|.:|:||||||||.|.||:|.||:|||.|
Worm   194 --TLFSDVEVDDWQDGSLEMVGLIEPGSFRALDDLVRNETKGHGRLEILSLKDVVEGE 249

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8549	NP_001261482.1	PTZ00448	4..>226	CDD:185627	125/224 (56%)
sbds-1	NP_497226.2	Sdo1	11..244	CDD:224417	133/236 (56%)
		SBDS	19..100	CDD:279511	59/80 (74%)
		SBDS_C	111..227	CDD:286465	48/119 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167693
Domainoid	1	1.000	138	1.000	Domainoid score	I3027
eggNOG	1	0.900	-	-		E1_COG1500
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6438
Inparanoid	1	1.050	279	1.000	Inparanoid score	I1768
Isobase	1	0.950	-	0	Normalized mean entropy	S584
OMA	1	1.010	-	-		QHG54247
OrthoDB	1	1.010	-	-		D1217666at2759
OrthoFinder	1	1.000	-	-		FOG0004811
OrthoInspector	1	1.000	-	-		oto17909
orthoMCL	1	0.900	-	-		OOG6_101125
Panther	1	1.100	-	-	LDO	PTHR10927
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1300
SonicParanoid	1	1.000	-	-		X3393
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	16	15.790