Protein Alignment velo and Senp3

DIOPT Version :10

• Sequence 1: NP_648056.1
• Gene: velo / 38748
• FlyBaseID: FBgn0035713
• Length: 1833
• Species: Drosophila melanogaster
• Sequence 2: NP_109627.3
• Gene: Senp3 / 80886
• MGIID: 2158736
• Length: 568
• Species: Mus musculus
• Alignment Length: 831
• Identity: 150/831 - (18%)
• Similarity: 241/831 - (29%)
• Gaps: 366/831 - (44%)

  Fly   938 TVSSAGSAG-ATPSEGRKLIDGFLAVCQLCGFTGVDHARCERCKRVFPEPPKRKS---------- 991
            |:...||.| ..|..|                |...:.|.||.:...|..|:.||
Mouse     4 TIQGTGSWGPEPPGPG----------------TTYSNPRRERLRWPLPPKPRLKSGGGFGPDPGS 52

  Fly   992 --YVPKNSAASSPASSSSSEPVSAVPTAADKKRELAAARFNNKMAGANFAVGVGVRGRG------ 1048
              .||.....:...|..:|..........:.:.|:||.|...:..    .:|...|.|.
Mouse    53 GTTVPTRRLPAPRPSFDASASEEEEEEEEEDEEEVAAWRLPPRWG----QLGASQRSRALRPSHR 113

  Fly  1049 -------SMAMRG-------------------GRARGGRRVPEVDPVVLLSSEDEAEGGEGTSDS 1087
                   ..|||.                   ||.||.|| ....|...||.:   |||.    :
Mouse   114 KTCSQRRRRAMRAFQMLLYSKSTSLTFHWKLWGRHRGRRR-NLAHPKNHLSPQ---EGGA----T 170

  Fly  1088 SNQPTNNSKLNSN--------GNLHELSA-----AFPCEPNLPEIDEEPLYKDFSRGDVRDLSDI 1139
            ...|:...:.:|.        |.|..|.|     ..|..|:.|.::|:.|         |.....
Mouse   171 PQVPSPCCRFDSPRGLPPPRLGLLGALMAEDGMRGSPPVPSGPPMEEDGL---------RWTPKS 226

  Fly  1140 PEADQFSASLKCSCVRLVPYRFEITEPVCFTTKGVRIAGILKDKDEKFELNIHKQEVIKVIAHFG 1204
            | .|..|..|.|:    :|..|               .|:...:.|:
Mouse   227 P-LDPDSGLLSCT----LPNGF---------------GGLSGPEGER------------------ 253

  Fly  1205 NVEPAQPLVTLYLLKTCA--EYVKNQLKLPDD----QHHEHTGFKTHSYHTRRLILLFDSISVSA 1263
              ..|.|..::.:...|:  ::|..:|....|    :..:.||.|...:...|
Mouse   254 --SLAPPDASILISNVCSIGDHVAQELFQSSDLGIAEEADRTGEKAGQHSPLR------------ 304

  Fly  1264 RGNIKSMFSCVDEI---------SSTDAAEILERIADSDRKTQDKSSQPPPRQLRADEQVSLLMY 1319
            ..::..:.|.:||.         .|||  |::|::.|.   .|.:.|.|..:.|    .:.|:..
Mouse   305 EEHVTCVQSILDEFLQTYGSLIPLSTD--EVVEKLEDI---FQQEFSTPSRKSL----VLQLIQS 360

  Fly  1320 PPKGTGGLCIR------------MEDFVCLTKESYLNDIIIDFYLLWLRNTLIPEPQRERTHIFS 1372
            ..:..|...:|            |:|...|..:::|||.:::.|     ..|:.:...|:.|.|:
Mouse   361 YQRMPGNAMVRGFRVSYKRHVLTMDDLGTLYGQNWLNDQVMNMY-----GDLVMDTVPEKVHFFN 420

  Fly  1373 TFFYKRLTTLTRPADMKQTAAQKRHARVQKWTKGVDIFDKDFIIVPINEQSHWFLAIICYPNLKG 1437
            :|||.:|.|             |.:..|::|||.||||:|:.:::||:.:.||.|
Mouse   421 SFFYDKLRT-------------KGYDGVKRWTKNVDIFNKELLLIPIHLEVHWSL---------- 462

  Fly  1438 PVTFDTNQPVEPQQLKRPRGKKVALQIGNTTITPLTKRAEGGQLPAALTAENVCRIADDESERDE 1502
                                  :::.:...|||
Mouse   463 ----------------------ISVDVRRRTIT-------------------------------- 473

  Fly  1503 AEGDESDMASEDSENSNSAKEPAATPTSTTASTPSLSSSQPTATGPARNIASDDVPAVKQPLILI 1567
                                                                            .
Mouse   474 ----------------------------------------------------------------Y 474

  Fly  1568 FDSLAGASRSRVVATLRDYLTCEYRVKKPDAQAHVFNKDNMPGH-------CVKVPQQNNFTDCG 1625
            |||....:| |....:..||           ||....||.:..|       .:.|.:|||.:|||
Mouse   475 FDSQRTLNR-RCPKHIAKYL-----------QAEAVKKDRLDFHQGWKGYFKMNVARQNNDSDCG 527

  Fly  1626 LYLLQYVEQFFGEPIRDYRLPIKQLTNWFDFLTVTKKREDIANLIQQLMDE 1676
            .::|||.:..             .|:..|.|     .::|:..|.:|:..|
Mouse   528 AFVLQYCKHL-------------ALSQPFSF-----TQQDMPKLRRQIYKE 560

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
velo	NP_648056.1	Peptidase_C48	1342..>1434	CDD:420019	28/91 (31%)
Senp3	NP_109627.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..119		25/134 (19%)
		Nuclear localization signal. /evidence=ECO:0000255	119..122		0/2 (0%)
		Nuclear localization signal. /evidence=ECO:0000255	147..153		3/5 (60%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	155..174		6/25 (24%)
		SENP3_5_N	<294..382	CDD:466160	19/108 (18%)
		Protease	380..537		56/314 (18%)
		Peptidase_C48	394..566	CDD:397169	60/343 (17%)