Protein Alignment velo and SENP7

DIOPT Version :9

• Sequence 1: NP_648056.1
• Gene: velo / 38748
• FlyBaseID: FBgn0035713
• Length: 1833
• Species: Drosophila melanogaster
• Sequence 2: XP_011511340.1
• Gene: SENP7 / 57337
• HGNCID: 30402
• Length: 1051
• Species: Homo sapiens
• Alignment Length: 1032
• Identity: 262/1032 - (25%)
• Similarity: 392/1032 - (37%)
• Gaps: 320/1032 - (31%)

  Fly   775 SHNNYEIHSQHVLNNRAGQEIAERDKNSAKMLVILASGEQR--------LITFTLPRE------S 825
            |:.|...|....|:.|..|.....|.||||...  .:.|:|        ||:.|.|.:      .
Human   212 SYQNLNPHKSCYLSERGSQRSKTVDDNSAKQTA--HNKEKRRKDDGISLLISDTQPEDLNSGSRG 274

  Fly   826 CTVQDLLEQVGVPFDHNTTIQCVEHRGANVDFVVTVGFTVHESASE--LISRAEESLQMNRSQEN 888
            |   |.|||              |.|..:|.:        .:|..|  ||||..:....|...::
Human   275 C---DHLEQ--------------ESRNKDVKY--------SDSKVELTLISRKTKRRLRNNLPDS 314

  Fly   889 QAAVAGAAAAANSNPATTSASPAYAQANAAAEQAKREAASSASGNTVVGTVSSAGSAGATPSEGR 953
            |...:                     .:.:.||.|::...|        |:|:...   .|||..
Human   315 QYCTS---------------------LDKSTEQTKKQEDDS--------TISTEFE---KPSENY 347

  Fly   954 KLIDGFLAVCQLCGFTGVDHARCERCKRVFPEPPKRKSYVPKNSAASSPASSSSSEPVSAVPTAA 1018
                               |..        |:.|:..:..|..|..:..:|.:|.|     .|.:
Human   348 -------------------HQD--------PKLPEEITTKPTKSDFTKLSSLNSQE-----LTLS 380

  Fly  1019 DKKRELAAARFNNKMAGANFAVGVGVRGRGSMAMRG-------------GRARGGRRVPEVDPVV 1070
            :..:..:|......:..:|   .:.:.|..|:..:.             |...|.:.:...:|:|
Human   381 NATKSASAGSTTETVENSN---SIDIVGISSLVEKDENELNTIEKPILRGHNEGNQSLISAEPIV 442

  Fly  1071 LLSSED---EAEGGE---GTSDSSNQPTNNSKLNSNGNLHEL-----------SAAFPCEPNLPE 1118
            :.|.|:   |.:..|   ..|....:.||.::..|...|.||           |...|..|.:..
Human   443 VSSDEEGPVEHKSSEILKLQSKQDRETTNENESTSESALLELPLITCESVQMSSELCPYNPVMEN 507

  Fly  1119 I------DEEPLYKDFSRGDVRDLSDIPEADQFSASLKCSCVRL------VPYRFEITE-PVCFT 1170
            |      :|..|..||....|. :..|..|.:       .||.:      :|::..:.| .:...
Human   508 ISSIMPSNEMDLQLDFIFTSVY-IGKIKGASK-------GCVTITKKYIKIPFQVSLNEISLLVD 564

  Fly  1171 TKGVRIAGILKDKDEKFELNIHK-----------QEVIKVIAHFGNVEPAQPLVTLYLLKTCAEY 1224
            |..::..|:.|.||:......|.           ||:...:.|          ..|......:|:
Human   565 TTHLKRFGLWKSKDDNHSKRSHAILFFWVSSDYLQEIQTQLEH----------SVLSQQSKSSEF 619

  Fly  1225 VKNQLKLPDDQHHEHTGFKTHSYHTRRLIL-----------------LFDSIS------------ 1260
            :..:|..|..|..|   .|.....|...|:                 ||.::|
Human   620 IFLELHNPVSQREE---LKLKDIMTEISIISGELELSYPLSWVQAFPLFQNLSSKESSFIHYYCV 681

  Fly  1261 ----------VSARGNIKSMFSCVDEISSTDAAE----ILERIADSDRKTQDKSSQPPP--RQLR 1309
                      |:....:||    |.:.|:||||:    .|:: ..|...:...:|.|..  |::|
Human   682 STCSFPAGVAVAEEMKLKS----VSQPSNTDAAKPTYTFLQK-QSSGCYSLSITSNPDEEWREVR 741

  Fly  1310 ADEQV-SLLMYPPKGT-GGLCIRMEDFVCLTKESYLNDIIIDFYLLWLRNTLIPEPQRERTHIFS 1372
            ....| .|::|||..| |||.:..||..||.:..:|||:||||||.:|......:...||:||||
Human   742 HTGLVQKLIVYPPPPTKGGLGVTNEDLECLEEGEFLNDVIIDFYLKYLILEKASDELVERSHIFS 806

  Fly  1373 TFFYKRLT----TLTRPADMKQTAAQKRHARVQKWTKGVDIFDKDFIIVPINEQSHWFLAIICYP 1433
            :||||.||    .||.. :...:.||:||.||:.||:.::||:||:|.||:||.|||:||:||:|
Human   807 SFFYKCLTRKENNLTED-NPNLSMAQRRHKRVRTWTRHINIFNKDYIFVPVNESSHWYLAVICFP 870

  Fly  1434 NLKGPVTFDTNQPVEPQQLKRPRGKKVALQIGNTTITPLTKRAEGGQLPAALTAENVCRIADDES 1498
            .|:..|..|..|.|                                                  |
Human   871 WLEEAVYEDFPQTV--------------------------------------------------S 885

  Fly  1499 ERDEAEGDESDMASEDSENSNSAKEPAATPTSTTASTPSLSSSQPTATGPARNIASDDVP--AVK 1561
            ::.:|:..::|..:.|::             ..|.||.|||:....:|.     ::..||  ..|
Human   886 QQSQAQQSQNDNKTIDND-------------LRTTSTLSLSAEDSQSTE-----SNMSVPKKMCK 932

  Fly  1562 QPLILIFDSLAGASRSRVVATLRDYLTCEYRVK-KPDAQAHVFNKDNMPGHCVKVPQQNNFTDCG 1625
            :|.|||.|||..||....|..||:||..|:.|| |...|   |:|.||...|.|||:|:|.:|||
Human   933 RPCILILDSLKAASVQNTVQNLREYLEVEWEVKLKTHRQ---FSKTNMVDLCPKVPKQDNSSDCG 994

  Fly  1626 LYLLQYVEQFFGEPIRDYRLPIKQLTNWFDFLTVTKKREDIANLIQQLMDEGNQQQR 1682
            :|||||||.||.:||.::.||| .|..||....:..|||||..||.:|   ..|||:
Human   995 VYLLQYVESFFKDPIVNFELPI-HLEKWFPRHVIKTKREDIRELILKL---HLQQQK 1047

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
velo	NP_648056.1	Peptidase_C48	1342..>1434	CDD:304959	48/95 (51%)
SENP7	XP_011511340.1	Peptidase_C48	775..1012	CDD:304959	111/308 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	160	1.000	Domainoid score	I4060
eggNOG	1	0.900	-	-		E1_COG5160
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S6692
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000929
OrthoInspector	1	1.000	-	-		otm51486
orthoMCL	1	0.900	-	-		OOG6_102905
Panther	1	1.100	-	-	LDO	PTHR46896
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1602
SonicParanoid	1	1.000	-	-		X756
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	10	9.840