DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment velo and senp5

DIOPT Version :9

Sequence 1:	NP_648056.1	Gene:	velo / 38748	FlyBaseID:	FBgn0035713	Length:	1833	Species:	Drosophila melanogaster
Sequence 2:	NP_001073666.2	Gene:	senp5 / 570299	ZFINID:	ZDB-GENE-050208-772	Length:	487	Species:	Danio rerio

Alignment Length:	618	Identity:	111/618 - (17%)
Similarity:	191/618 - (30%)	Gaps:	229/618 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   940 SSAGSAGATPSEGRKLIDGFLAVCQLCGFTGVDHARCERCKRVFPEPPKRKSYVPKNSAASSPAS 1004
            :.:|| |..|..||.........|..||                   |..|.::|.:...|....
Zfish    12 AESGS-GKMPENGRSRRKRVPKTCDCCG-------------------PNGKPHMPGHEQVSKKRG 56

  Fly  1005 SSSSEPVSAVPTAADKKRELAAARFNNKMAGANFAVGVGVRGRGSMAMRGGRARGGRRVPEVDPV 1069
            ....|.||....||:::...:.:                    |.:.:            |.|.|
Zfish    57 RKKKEMVSQGEVAAEEEVVWSTS--------------------GVLTL------------EADAV 89

  Fly  1070 VL-LSSEDEAEG------GEGTSDSS-------NQPTNNSKLNSNGNLHELSAAFPCEPNLPEID 1120
            .. :....:|.|      .|..|||:       |...:|....:..|.|.:.||   ...|.::.
Zfish    90 TAEMEETPDARGKADFIQSESVSDSTVMVNGLENSAHDNCTDPAKENSHPVQAA---SALLNDLM 151

  Fly  1121 EEPLYKDFSRGDVRDLSDIPEADQFSASLKCSCVRLVPYRFEITEP--VCFTTKGVRIAGILKDK 1183
            ::|       .|...::..|:|...|.:::             |||  :|     ||:
Zfish   152 KKP-------SDSASVAAEPDASPHSNAME-------------TEPSSLC-----VRV------- 184

  Fly  1184 DEKFELNIHKQEVIKVIAHFGNVEPAQPLVTLYLLKTCAEYVKNQLKLPDDQHHEHTGFKTHSYH 1248
                                                             |....:|...|::...
Zfish   185 -------------------------------------------------DKASWDHHYCKSNPAE 200

  Fly  1249 TRRLILLFDSISVS----ARGNIKSMFSCVDE--------------ISSTDAAEILERIADSDRK 1295
            .|.     ||...|    |....:.:..|:.|              :..||..:.|.:|..:|..
Zfish   201 NRS-----DSAEASGPPPAEFTSEGIIDCIHEFLEQFYGKYGSFTPLCETDVLDHLNKIFQADLN 260

  Fly  1296 TQDKSSQPPPRQLRAD---EQVSLLMYPPKGTGGLCIRMEDFVCLTKESYLNDIIIDFYLLWLRN 1357
            .:.|.......:.||.   ..:.|.:...|.|    :.:||...|..::::||.:|:.|     .
Zfish   261 DRMKLITAEVAKYRAGLACAPMHLQVTYNKHT----LSLEDLSTLDDQNWVNDQVINMY-----G 316

  Fly  1358 TLIPEPQRERTHIFSTFFYKRLTTLTRPADMKQTAAQKRHARVQKWTKGVDIFDKDFIIVPINEQ 1422
            .||.|......|.|::|||::...             |.:..|::|||.||:|.|..|::|::.:
Zfish   317 ELIMEATNHTVHFFNSFFYRQFVA-------------KGYEGVRRWTKKVDLFSKTLILIPLHLE 368

  Fly  1423 SHWFLAIICYPNLKGPVTFDTNQPV---------------EPQQLKRPRGKKVALQIGNTTITPL 1472
            .||  ::|.....|..:.|..:|.:               |.::.|:|..:|....:.|.||...
Zfish   369 IHW--SLITVDVSKQNINFYDSQGILFKFALDNVMKYIMEEAKEKKQPLFQKGWKMLINKTIPQQ 431

  Fly  1473 TKRAEGGQL------------PAALTAENVCRI 1493
            ....:.|..            |.:.|.|::.|:
Zfish   432 KNDNDCGAFVLEYCKCLAFMKPLSFTQEDMPRV 464

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
velo	NP_648056.1	Peptidase_C48	1342..>1434	CDD:304959	26/91 (29%)
senp5	NP_001073666.2	Peptidase_C48	305..477	CDD:280975	41/180 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5160
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810