Protein Alignment velo and SENP1

DIOPT Version :10

• Sequence 1: NP_648056.1
• Gene: velo / 38748
• FlyBaseID: FBgn0035713
• Length: 1833
• Species: Drosophila melanogaster
• Sequence 2: XP_016874718.1
• Gene: SENP1 / 29843
• HGNCID: 17927
• Length: 707
• Species: Homo sapiens
• Alignment Length: 805
• Identity: 155/805 - (19%)
• Similarity: 272/805 - (33%)
• Gaps: 249/805 - (30%)

  Fly   750 PVPAAVAAPIPAPAAVTQGSSVMKTSHNNYEIHSQHVLNNRAGQEIAERDKNSAKM--------- 805
            |:.|.:..|..:|..:...:.|  :.....|:.::..|.::||.|:.....:||..
Human     4 PLTATICLPGSSPPGLCIFAKV--SDVKRLEMETRFCLISQAGLELLGSSHSSASASQSASITDD 66

  Fly   806 ---LVILASGEQRLITFTLPRESCTVQDLLEQVGVPFDHNTTIQCVEHRGANVDFVVTVGFTVHE 867
               .:.:.:||..|:.    ..|.....||.|.|.|.|.
Human    67 IADRMRMDAGEVTLVN----HNSVFKTHLLPQTGFPEDQ-------------------------- 101

  Fly   868 SASELISRAEESLQMNRSQENQAAVAGAAAAANSNPATTSASPAYAQANAAAEQAKREAASSASG 932
                 :|.:::.:..:|......:...:..:|..||:..|.:|:......:.:  .|....||:|
Human   102 -----LSLSDQQILSSRQGHLDRSFTCSTRSAAYNPSYYSDNPSSDSFLGSGD--LRTFGQSANG 159

  Fly   933 NTVVGTVSSAGSAGATPS------EGRKLIDGFLAVCQLCGFTGVDHARC--ERCKRVFPEPPKR 989
            .....|.||:.|...:.:      |.||...|...     .|.|..:..|  ...::.||..|
Human   160 QWRNSTPSSSSSLQKSRNSRSLYLETRKTSSGLSN-----SFAGKSNHHCHVSAYEKSFPIKP-- 217

  Fly   990 KSYVPKNS-------AASSPASSSSSEPVSAVPTAADKKRELAAARFNNKMAGANFAVGVGVRGR 1047
               ||..|       :..||..:......:|..|..:::||: ..:....:.|..|.:
Human   218 ---VPSPSWSGSCRRSLLSPKKTQRRHVSTAEETVQEEEREI-YRQLLQMVTGKQFTI------- 271

  Fly  1048 GSMAMRGGRARGGRRVPEVDPVVLLSSEDEAEG--------------GEGTSDSSNQP--TNNSK 1096
                     |:.....|......|.||::..:.              |..||.|.:..  ||..:
Human   272 ---------AKPTTHFPLHLSRCLSSSKNTLKDSLFKNGNSCASQIIGSDTSSSGSASILTNQEQ 327

  Fly  1097 LNSNGNLHELSAAFPCEPNLPEIDEEPLYKDFSRGDVRDLSDIPEADQFSASLKCSCVRLVPYRF 1161
            |:.  :::.||:..|               |.:.|. :|...:.......:         ||::.
Human   328 LSH--SVYSLSSYTP---------------DVAFGS-KDSGTLHHPHHHHS---------VPHQP 365

  Fly  1162 EITEPVCFTTKGVRIAGILKDKDEK--------FELNIHKQEVIKVIAHFGNVEPAQPLVTLYLL 1218
            :........::|.....:||.||.:        |:..:..:|:..|.    :....:.|..:...
Human   366 DNLAASNTQSEGSDSVILLKVKDSQTPTPSSTFFQAELWIKELTSVY----DSRARERLRQIEEQ 426

  Fly  1219 KTCAEYVKNQLKLPDDQHHEHTGFKTHSYHTRRLILLFDSISVSARGNIKSMFSCVDEISSTDAA 1283
            |..|..::|| :|.:.:|..|                 ||:.:..|..::.      ||..|...
Human   427 KALALQLQNQ-RLQEREHSVH-----------------DSVELHLRVPLEK------EIPVTVVQ 467

  Fly  1284 EILE---RIADSD------RKTQDKSSQPPPRQLRADEQVSLLMYPPKGTGGLCIRMEDFVCLTK 1339
            |..:   ::.||:      .:..:|..:...|....||.:|...       .|.|..:|...|..
Human   468 ETQKKGHKLTDSEDEFPEITEEMEKEIKNVFRNGNQDEVLSEAF-------RLTITRKDIQTLNH 525

  Fly  1340 ESYLNDIIIDFYLLWLRNTLIPEPQRER----THIFSTFFYKRLTTLTRPADMKQTAAQKRHARV 1400
            .::|||.||:||:     .::.|..:|:    .|.|:|||:.:|.|....|             |
Human   526 LNWLNDEIINFYM-----NMLMERSKEKGLPSVHAFNTFFFTKLKTAGYQA-------------V 572

  Fly  1401 QKWTKGVDIFDKDFIIVPINEQSHWFLAI-------ICYPNLKGPVT------------------ 1440
            ::|||.||:|..|.::|||:...||.||:       |.|.:..|.:.
Human   573 KRWTKKVDVFSVDILLVPIHLGVHWCLAVVDFRKKNITYYDSMGGINNEACRILLQYLKQESIDK 637

  Fly  1441 ----FDTN---------QPVEPQQL 1452
                ||||         |.: |||:
Human   638 KRKEFDTNGWQLFSKKSQEI-PQQM 661

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
velo	NP_648056.1	Peptidase_C48	1342..>1434	CDD:420019	34/102 (33%)
SENP1	XP_016874718.1	Peptidase_C48	<483..705	CDD:420019	52/205 (25%)