Protein Alignment velo and Semp2l2a

DIOPT Version :10

• Sequence 1: NP_648056.1
• Gene: velo / 38748
• FlyBaseID: FBgn0035713
• Length: 1833
• Species: Drosophila melanogaster
• Sequence 2: NP_694733.3
• Gene: Semp2l2a / 231201
• MGIID: 2667157
• Length: 502
• Species: Mus musculus
• Alignment Length: 544
• Identity: 111/544 - (20%)
• Similarity: 185/544 - (34%)
• Gaps: 190/544 - (34%)

  Fly   921 QAKREAASSASGNT-----VVGTVSSAGSAGATPSEGRKLIDGFLAVCQLCGFTGVDHARCERCK 980
            :.|.||  ||.|.|     ..||...:.:.|..|.  ||..||          :|:
Mouse    10 EMKPEA--SAIGQTRKYHDESGTEIESEALGQEPK--RKCQDG----------SGM--------- 51

  Fly   981 RVFPEP---PKRKSYVPKN--SAASSPASSSSSEPVSAVPTAADKKRELAAARFNNKMAGANFAV 1040
             ||.||   .|:.|..|::  .....|:.....:|....|... |..||........:.|...|.
Mouse    52 -VFKEPGKAQKKTSQEPQDLELPREQPSKGQVRKPQGKTPKQL-KPLELTEGPPEQAVTGRKPAD 114

  Fly  1041 GVGVRGRGSMAMRGG-----RARGGR-----------RVPEVDPVVLLSSEDEAEGGEGTSDSSN 1089
            |.....|....|...     :.:.||           |..:..|..:|::..:.:|||     |.
Mouse   115 GGKGHKRPYSVMEENEQSPQKEKYGRLLQHLQCDQDVRSDQHRPHPILTNTWKIKGGE-----SG 174

  Fly  1090 QPTNNSKLNSNGNLHELSAAFPCEPNLPEIDEEPLYKDFSRGDVRDLSDIPEADQFSASLKCSCV 1154
            ....:.::.||.....::|...|                       ||  ||..:     || |
Mouse   175 DSHGSERIQSNREPSTVAALKEC-----------------------LS--PEGRE-----KC-C- 207

  Fly  1155 RLVPYRFEITEPVCFTTKGVRIAGILKDKDEKFELNIHKQEVIKVIAHFGN-VEPAQPLVTLYLL 1218
                     :|..|.|.|    .|.:|.:..:                 || :||..|
Mouse   208 ---------SEEKCVTEK----KGCVKGEGRR-----------------GNSLEPDLP------- 235

  Fly  1219 KTCAEYV----KNQLKLPDDQHHEHTGFKTHSYHTRRLILLFDSISVSARGNIKSMFSCVDEISS 1279
            :|.|:.:    :....||:                :..:|..:...::.:|..:.|...:|
Mouse   236 ETWAQIILDSGRGNSLLPN----------------KVAVLAAEKKPITDQGKGRKMDQILD---- 280

  Fly  1280 TDAAEILERIADSDRKTQDKSSQPPPRQLRADEQVSLLMYPPKGTGGLCIRMEDFVCLTKESYLN 1344
                     |::...|..:.:..|.|::.....:..|.           |...|...|....:||
Mouse   281 ---------ISEDMEKEIENALGPGPQEEILSSRFKLQ-----------ISRGDIQTLENGQWLN 325

  Fly  1345 DIIIDFYLLWLRNTLIPEPQRE---RTHIFSTFFYKRLTTLTRPADMKQTAAQKRHARVQKWTKG 1406
            |.:|:||:    |.|:...:.:   ..|:||||||.:|             ....::.|::||:|
Mouse   326 DEVINFYM----NLLVERNENQGYPALHVFSTFFYPKL-------------KHSGYSSVKRWTRG 373

  Fly  1407 VDIFDKDFIIVPINEQSHWFLAII 1430
            :::|:|:.|:|||:::.||.|.:|
Mouse   374 INLFEKELILVPIHQRVHWSLVVI 397

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
velo	NP_648056.1	Peptidase_C48	1342..>1434	CDD:420019	30/92 (33%)
Semp2l2a	NP_694733.3	Peptidase_C48	<279..497	CDD:420019	39/160 (24%)