Protein Alignment velo and Senp6

DIOPT Version :10

• Sequence 1: NP_648056.1
• Gene: velo / 38748
• FlyBaseID: FBgn0035713
• Length: 1833
• Species: Drosophila melanogaster
• Sequence 2: NP_001298039.1
• Gene: Senp6 / 215351
• MGIID: 1922075
• Length: 1139
• Species: Mus musculus
• Alignment Length: 1175
• Identity: 275/1175 - (23%)
• Similarity: 452/1175 - (38%)
• Gaps: 318/1175 - (27%)

  Fly   768 GSSVMKTSHNNYEIHSQHVLNNRAGQEIAERDKNSAKMLVILASGEQRLITFTLPRESCTVQDLL 832
            |::::.....:.||.....||.|:             .:|..:||:..|.|:.  |.|.|  |..
Mouse    49 GANLLSVEDEDSEISKGKKLNRRS-------------EIVATSSGDFILKTYV--RRSKT--DGF 96

  Fly   833 EQV-GVPFDHNTTIQCVEHRGANVDFVVTVGFTVH-------ESASELISRAEESLQMNRSQ--- 886
            :.: |.|...|......:...:.....:..|..||       .|.:..|..|.:|.|..:.:
Mouse    97 KTLKGNPIGLNMLSNNKKLSESTAGTALCSGTVVHGRRFHHAHSQTPGIRTAAQSNQDRKERKEY 161

  Fly   887 -------ENQAAVAGAAAAANSNPATTSASPAYAQANAAAE-QAKREAASSASGNTVVGTVSSAG 943
                   ||...:.......:.....|..|.:|.::....: |.||..::..     :..:|.|.
Mouse   162 PPYVHKAENSPVMLSHGQGGDHIMKKTEESESYVESEIKRKVQQKRHCSTYQ-----LSPLSPAS 221

  Fly   944 SAGAT---PSEGRKLIDGFLAVCQLCGFTGVDHARCERCKRVF----------------PEPPKR 989
            ....|   .||.|:       .|..||....:..:|:.|..||                |..|..
Mouse   222 KKCLTHLEVSEQRE-------YCPKCGKEKENQTKCQSCGIVFHNDLQRNCRQAVTLNEPTGPLL 279

  Fly   990 KSYVPKNSAASSP-----------ASSSSSEPVSAVPTAADKKRELAAARFNNKMAGANFAVGVG 1043
            ::.:.:||.....           .:|....|:..:.|..|.:.              |:
Mouse   280 RTSIHQNSGGQKSQNTGLTAKKFYGNSVDKIPIDILVTCDDSRH--------------NY----- 325

  Fly  1044 VRGRGSMAMRGGRARGGRRVPEV--------------DPVVLLSSEDEAEGG-----EGTSDSSN 1089
            ::..|.:.:.||      ::|::              ||::|.|.:|:.:..     |.||....
Mouse   326 IQTNGKVILPGG------KIPKLTNPKERKISVSDLNDPIILSSDDDDDDDDRTKRRESTSPKPA 384

  Fly  1090 QPTNNSKLNSNGNLH-ELSA----------AFPCEPNLPE--IDEEPLYKD---------FSRGD 1132
            ....:|.:.|.|.:. .|:|          :.|.||.|..  |..:...||         ..|..
Mouse   385 DSACSSPVPSTGKVEAALNADACRAEQEPRSSPAEPELNTIVIPRKARMKDQLGNSISTPLKRRK 449

  Fly  1133 VR---------DLSDIPEADQF-SASLKCSCVRLVPYRFEITEPVCFTTKGVRIAGILKDKDEKF 1187
            |.         .||    ...| |..|.|..:|:......:.|||.|:.:.:.|
Mouse   450 VNSHAAFIHPMSLS----CQNFESVILNCRSIRVGTLFRLLVEPVIFSLESITI----------- 499

  Fly  1188 ELNIHKQEVIKVIAHFGNVEPAQ-------PLVTLYLLKTCAEYVKNQLKL--PDDQHHEHTG-- 1241
            .|:..:.:.:.:|.:..::...:       |:|.|..:....:.:..||::  .|...::..|
Mouse   500 HLDGPESDPVDIILNTSDLTKCEWCNVRKLPVVFLQAIPAVYQKLSMQLQMSKEDKVWNDCKGIN 564

  Fly  1242 -------------FKTHSYHTRRLILLFDSI--SVSARGNIKSMFSCV--DEISSTDAA------ 1283
                         |:|...|...::  |:||  .:..|.|:.:.|:.:  ||.:|...|
Mouse   565 RITSLEEQYIILIFQTGLDHQAEVV--FESIITDIGIRNNVPNFFAKILFDEANSRLVACTRSYE 627

  Fly  1284 -EILERIADSDRKTQDKSSQPPPRQLRADEQV---------------------SLLMY-PPKGTG 1325
             .|....|..:.|.:..|.: ...|||:.:::                     .|::| ||...|
Mouse   628 ESIKGNCAQKENKVKTVSFE-SKIQLRSKQELQFFDDDEEAGESHTIFIGPVEKLIVYPPPPAKG 691

  Fly  1326 GLCIRMEDFVCLTKESYLNDIIIDFYLLWLRNTLIPEPQRERTHIFSTFFYKRLTTLTR--PADM 1388
            |:.:..||..||::..:|||:||||||.:|....:.:...:|.||||:||||||....|  |...
Mouse   692 GISVTNEDLHCLSEGEFLNDVIIDFYLKYLVLEKLKKEDADRIHIFSSFFYKRLNQRERRNPETT 756

  Fly  1389 KQTAAQKRHARVQKWTKGVDIFDKDFIIVPINEQSHWFLAIICYPNLKGPVTFDTNQPVEPQQL- 1452
            ..:..||||.||:.||:.||||:||||.||:||.:|||||::|:|.|:.| .::.|.......:
Mouse   757 NLSIQQKRHGRVKTWTRHVDIFEKDFIFVPLNEAAHWFLAVVCFPGLEKP-KYEPNPHYHENAVM 820

  Fly  1453 -KRPRGK----KVALQIG----NTTITPLTKRAEGGQLPAALTAENVCRIADDESERDEAEG--- 1505
             |.|..:    ..|.::|    |:...|:.|:        .|..::...:.|..:.::|:|.
Mouse   821 QKTPSAEDSCVSSASEMGACSQNSAAKPVIKK--------MLNRKHCLAVTDSSAAQEESEPCYR 877

  Fly  1506 ----------DESDMASEDSENSNSAKEPAATPTSTTASTPSL------SSSQPTATGPAR---- 1550
                      .:.:.|..::|..::.:.........|.|...|      |...|.|....|
Mouse   878 RNAYSVKCSMKKKNHAINENEEPSNGESTCQDICDRTQSENGLRDECFSSVHHPDALSKIRLNYG 942

  Fly  1551 ------------------------NIASDD-----------------VPAV-KQPLILIFDSLAG 1573
                                    :.:|||                 .|.| |||.||:.|||.|
Mouse   943 DQSADGGKLLEDELIDFSEDQDDPDDSSDDGLLADENYSSEIGQWHLKPTVCKQPCILLMDSLRG 1007

  Fly  1574 ASRSRVVATLRDYLTCEYRVKKPDAQAHVFNKDNMPGHCVKVPQQNNFTDCGLYLLQYVEQFFGE 1638
            .|||.||..||:||..|:.|||...::  |:||.|.|...||||||||:|||:|:|||||.||..
Mouse  1008 PSRSNVVKILREYLEVEWEVKKGSKRS--FSKDVMKGSNPKVPQQNNFSDCGVYVLQYVESFFEN 1070

  Fly  1639 PIRDYRLPIKQLTNWFDFLTVTKKREDIANLIQQLMDEGNQQQRLILPVIEFPTLNGQLVEYPED 1703
            |:.::.||: .|.|||....:..|||:|.|:|.:|.:..::.::|:...:...:|.....:|...
Mouse  1071 PVLNFELPM-NLMNWFPPPRMKTKREEIRNIILKLQESQSKDKKLLKDSLAETSLGDGAEQYASA 1134

  Fly  1704 TESAE 1708
            :..:|
Mouse  1135 SGGSE 1139

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
velo	NP_648056.1	Peptidase_C48	1342..>1434	CDD:420019	49/93 (53%)
Senp6	NP_001298039.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	23..51		1/1 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	334..395		12/66 (18%)
		Protease	693..1139		145/457 (32%)
		Peptidase_C48	707..>819	CDD:420019	53/112 (47%)
		Peptidase_C48	<999..1075	CDD:420019	44/77 (57%)