DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dikar and tbrd-3

DIOPT Version :9

Sequence 1:	NP_001261480.1	Gene:	dikar / 38747	FlyBaseID:	FBgn0261934	Length:	3261	Species:	Drosophila melanogaster
Sequence 2:	NP_726307.1	Gene:	tbrd-3 / 246604	FlyBaseID:	FBgn0050417	Length:	268	Species:	Drosophila melanogaster

Alignment Length:	251	Identity:	56/251 - (22%)
Similarity:	96/251 - (38%)	Gaps:	70/251 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   887 ETEEVL-QIGMHKVLV---YVKNHRD-AWPFVDPVEEDI--APRYYSIIRRPMDLLKMEDKLDSG 944
            |||... :|...||::   :...::: ||.|.:|::..:  ...|:.|:|.||||..:..:|::|
  Fly     6 ETERSSPEINACKVIIKRLFSSTYKNIAWVFYEPLDPQLLGLHDYHEIVREPMDLSTVRHRLNTG 70

  Fly   945 EYHKFSEFRNDFRLIVNNCRLYNGHNNEYTEMVNNLQDAFEKATKKYFDNLSDDEDDDPNLSYPA 1009
            .|...::|..|.|||..|..||...::....|...||..||:...:.            .|...:
  Fly    71 CYLSAADFAKDIRLIFYNTYLYTNPDHLCYHMAKQLQIIFEEMYSQV------------QLYICS 123

  Fly  1010 ADSKMNVFREKYFSKKAKEETEKDAPGRPAVSSAEEDLSEIEAE-----APQKAQKRKRKEKDKR 1069
            :.||:          :|:||:..|....   ||.|::::..|..     ||.....
  Fly   124 SGSKV----------RAEEESSSDESDS---SSPEDEVNGSEVSPSIMGAPPSCTP--------- 166

  Fly  1070 RKKKTKSKADVETDDEDMEAEREPTPPPPPPTSKKSKTSKTGKEKEKDKEKEKDKD 1125
                              ..|..|||...||.:.::      .|:::....|:|.|
  Fly   167 ------------------TTECTPTPDWTPPATLET------SEQQEPFTTEEDLD 198

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dikar	NP_001261480.1	WHIM1	100..148	CDD:292246
dikar	NP_001261480.1	Bromo_gcn5_like	892..991	CDD:99941	30/105 (29%)
tbrd-3	NP_726307.1	Bromo_Brdt_II_like	13..114	CDD:99930	30/100 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5076
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900