DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dikar and F13C5.2

DIOPT Version :9

Sequence 1:	NP_001261480.1	Gene:	dikar / 38747	FlyBaseID:	FBgn0261934	Length:	3261	Species:	Drosophila melanogaster
Sequence 2:	NP_508124.1	Gene:	F13C5.2 / 180410	WormBaseID:	WBGene00017423	Length:	374	Species:	Caenorhabditis elegans

Alignment Length:	233	Identity:	59/233 - (25%)
Similarity:	102/233 - (43%)	Gaps:	56/233 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   902 YVKNHRDA--WPFVDPVEEDI--APRYYSIIRRPMDLLKMEDKLDSGEYHKFSEFRNDFRLIVNN 962
            :.|:..|:  :||..||:..:  ...|:.:|::|||:..:..||...||....||:.||:|::||
Worm   129 FEKSTHDSFTFPFRKPVDVVLLGLTDYHEVIKKPMDMSTIRKKLIGEEYDTAVEFKEDFKLMINN 193

  Fly   963 CRLYNGHNNEYTEMVNNLQDAFEKATKKYF----DNL---------SDDEDDDPNLSYPAADSKM 1014
            |..||...:...:.....:..|....||.|    |:.         ||:|||:
Worm   194 CLTYNNEGDPVADFALQFRKKFAAKWKKEFPEDGDSFGQEKGEKEGSDNEDDE------------ 246

  Fly  1015 NVFREKYFSKKAKEETEKDAPGRPAVSSAEEDLSEIEAEAPQKAQKRKRKEKDKRRKKKTKSKAD 1079
                |:...|:.:||.::|        :|||..:| |.|.|.  :|.:...:|:|.:::.:..:|
Worm   247 ----EEVDEKEKEEEVKED--------NAEEKPAE-EPEQPD--EKEEEDHEDEREEQEEEDSSD 296

  Fly  1080 VE--TDDEDME----------AEREPTPPPPPPTSKKS 1105
            .|  .||:|:.          ..:.|....|.|.::.|
Worm   297 EEDGLDDDDVRRHIPASTSAPVAKHPEAAMPEPAAEHS 334

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dikar	NP_001261480.1	WHIM1	100..148	CDD:292246
dikar	NP_001261480.1	Bromo_gcn5_like	892..991	CDD:99941	27/92 (29%)
F13C5.2	NP_508124.1	Bromodomain	118..219	CDD:383021	26/89 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900