Protein Alignment ple and Trh

DIOPT Version :9

• Sequence 1: NP_001286955.1
• Gene: ple / 38746
• FlyBaseID: FBgn0005626
• Length: 579
• Species: Drosophila melanogaster
• Sequence 2: NP_612080.1
• Gene: Trh / 38121
• FlyBaseID: FBgn0035187
• Length: 555
• Species: Drosophila melanogaster
• Alignment Length: 499
• Identity: 193/499 - (38%)
• Similarity: 290/499 - (58%)
• Gaps: 34/499 - (6%)

  Fly   107 FESVEQEQSESQSQEPEGNQQPTKNDYGLTEDEILLANAASESSDAEAAM--------------Q 157
            :.|.|||.:..|. .|....:......|.:....|..||::.......|:              :
  Fly    14 YRSGEQEWAVKQG-SPLHQLKKDSTTSGSSSHPSLGRNASAPPEPPRLAIGGGGQDNGRQHSPGE 77

  Fly   158 SAALVVRLKEGISSLGRILKAIETFHGTVQHVESRQSRVEGVDHDVLIKLDMTRGNLLQLIRSLR 222
            ..:::..|:..:.:|.|.|:..:.....|.|:|.....:.....|||:.::..:..|.|:::.|.
  Fly    78 RISIIFTLRNQVGNLARALQVFQELGINVLHLELSPLEMATNQADVLVDVECDQRRLDQVVKMLN 142

  Fly   223 QSGSFSSMNLMADNNLNV-KAP--------------WFPKHASELDNCNHLMTKYEPDLDMNHPG 272
            :  ..:|:|..:.|...: :||              |||:..|:||...::: .|..:||.:|||
  Fly   143 R--EVASVNYTSVNTQGLARAPSLSACSSFDFGDMVWFPRKISDLDKAQNVL-MYGSELDADHPG 204

  Fly   273 FADKVYRQRRKEIAEIAFAYKYGDPIPFIDYSDVEVKTWRSVFKTVQDLAPKHACAEYRAAFQKL 337
            |.|.|||:||::.:.||..:|:|:|||.:.|:..|||||.:||..:..|...||..||...:.:|
  Fly   205 FKDPVYRKRREQFSAIANNFKHGNPIPRVQYTPEEVKTWGTVFLELHRLYVLHAVPEYMDNWPEL 269

  Fly   338 QDEQIFVETRLPQLQEMSDFLRKNTGFSLRPAAGLLTARDFLASLAFRIFQSTQYVRHVNSPYHT 402
            :....:.|..:||||::|.:|::.|||.|||.||.|:.||||:.||||:|..|||:||.:.|::|
  Fly   270 EKYCGYREDNVPQLQDVSVYLKRKTGFQLRPVAGYLSPRDFLSGLAFRVFHCTQYIRHSSDPFYT 334

  Fly   403 PEPDSIHELLGHMPLLADPSFAQFSQEIGLASLGASDEEIEKLSTVYWFTVEFGLCKE-HGQIKA 466
            ||||..|||||||||||:.||||||||||||||||||.:||||:|:|:|||||||||: ....|.
  Fly   335 PEPDCCHELLGHMPLLANSSFAQFSQEIGLASLGASDADIEKLATLYFFTVEFGLCKQADSTFKV 399

  Fly   467 YGAGLLSSYGELLHAISDKCEHRAFEPASTAVQPYQDQEYQPIYYVAESFEDAKDKFRRWVSTMS 531
            ||||||||..||.|||:.:.:.:.|:|..|..|......||..||..:|||:||::.|.:..::.
  Fly   400 YGAGLLSSVAELQHAITAENKIKKFDPEVTCQQECIITSYQNAYYYTDSFEEAKEQMRAFAESIQ 464

  Fly   532 RPFEVRFNPHTERVEVLDSVDKLETLVHQMNTEILHLTNAISKL 575
            |||.||:||:|..||||.:..|:..:|.::..::..:.:|:.|:
  Fly   465 RPFGVRYNPYTMSVEVLSNAKKITAVVSELRGDLSIVCSALRKI 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ple	NP_001286955.1	Tyr_3_monoox	130..576	CDD:130336	187/476 (39%)
		ACT	130..234	CDD:298841	20/117 (17%)
		Biopterin_H	243..573	CDD:278766	164/344 (48%)
Trh	NP_612080.1	Trp_5_monoox	34..509	CDD:130337	187/478 (39%)
		ACT_TPH	79..152	CDD:153201	15/74 (20%)
		Biopterin_H	177..506	CDD:278766	163/329 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45449663
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3186
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D361696at33208
OrthoFinder	1	1.000	-	-		FOG0000587
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11473
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.850