Protein Alignment ple and pah-1

DIOPT Version :9

• Sequence 1: NP_001286955.1
• Gene: ple / 38746
• FlyBaseID: FBgn0005626
• Length: 579
• Species: Drosophila melanogaster
• Sequence 2: NP_001254185.1
• Gene: pah-1 / 174401
• WormBaseID: WBGene00000240
• Length: 457
• Species: Caenorhabditis elegans
• Alignment Length: 448
• Identity: 203/448 - (45%)
• Similarity: 290/448 - (64%)
• Gaps: 11/448 - (2%)

  Fly   137 EDEILLANAASES--SDAEAAMQSAALVVRLKEGISSLGRILKAIETFHGTVQHVESRQSRVEGV 199
            :|::.....|.||  :|..|.:....:|..|:|...:|...||..:.....:.|:|||.|:....
 Worm     6 QDDLDFLKYAMESYVADVNADIGKTTIVFTLREKAGALAETLKLFQAHDVNLSHIESRPSKTHEG 70

  Fly   200 DHDVLIKLDMTRGN--LLQLIRSLRQSGSFSSMNLMADNNLNVK-----APWFPKHASELDNCNH 257
            .::||::......:  :..:|...:|..  ....|:.|.|...|     .||||:..:::|...:
 Worm    71 CYEVLVEFAEAEDHRKIEGVIEHFQQKA--EKKVLVQDWNTKNKQNKDSVPWFPQKINDIDQFAN 133

  Fly   258 LMTKYEPDLDMNHPGFADKVYRQRRKEIAEIAFAYKYGDPIPFIDYSDVEVKTWRSVFKTVQDLA 322
            .:..|..:||.:||||.|..||:|||..|:|||.:|:||.||.|.|:|.|:.|||:|:..:..:.
 Worm   134 RILSYGAELDADHPGFKDMTYRERRKFFADIAFNFKHGDKIPTITYTDEEIATWRTVYNELTVMY 198

  Fly   323 PKHACAEYRAAFQKLQDEQIFVETRLPQLQEMSDFLRKNTGFSLRPAAGLLTARDFLASLAFRIF 387
            ||:||.|:...|..||....|...|:||||::||||:..||:::||.||||::|||||.||||:|
 Worm   199 PKNACQEFNYIFPLLQQNCGFGPDRIPQLQDVSDFLKDCTGYTIRPVAGLLSSRDFLAGLAFRVF 263

  Fly   388 QSTQYVRHVNSPYHTPEPDSIHELLGHMPLLADPSFAQFSQEIGLASLGASDEEIEKLSTVYWFT 452
            .||||:||.::|.:|||||..||||||:||.||..|||||||||||||||.|:.||||:|:||||
 Worm   264 HSTQYIRHHSAPKYTPEPDICHELLGHVPLFADVEFAQFSQEIGLASLGAPDDVIEKLATLYWFT 328

  Fly   453 VEFGLCKEHGQIKAYGAGLLSSYGELLHAISDKCEHRAFEPASTAVQPYQDQEYQPIYYVAESFE 517
            :|||:|::.|:.||||||||||:|||.:|:|||.|...|:||...|..|...||||.|::||||.
 Worm   329 IEFGICQQDGEKKAYGAGLLSSFGELQYALSDKPEVVDFDPAVCCVTKYPITEYQPKYFLAESFA 393

  Fly   518 DAKDKFRRWVSTMSRPFEVRFNPHTERVEVLDSVDKLETLVHQMNTEILHLTNAISKL 575
            .||:|.:.|.:|::|||::|:|.:|:|||:||.|..|:.|...:.::|..|..|:.|:
 Worm   394 SAKNKLKSWAATINRPFQIRYNAYTQRVEILDKVAALQRLARDIRSDISTLEEALGKV 451

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ple	NP_001286955.1	Tyr_3_monoox	130..576	CDD:130336	203/448 (45%)
		ACT	130..234	CDD:298841	22/100 (22%)
		Biopterin_H	243..573	CDD:278766	177/329 (54%)
pah-1	NP_001254185.1	Phe4hydrox_tetr	15..452	CDD:130335	202/439 (46%)
		ACT_AAAH	30..99	CDD:153176	15/70 (21%)
		Biopterin_H	119..448	CDD:278766	176/328 (54%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D361696at33208
OrthoFinder	1	1.000	-	-		FOG0000587
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.920