DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8519 and Rergl

DIOPT Version :9

Sequence 1:	NP_648054.2	Gene:	CG8519 / 38745	FlyBaseID:	FBgn0035711	Length:	207	Species:	Drosophila melanogaster
Sequence 2:	NP_001121562.1	Gene:	Rergl / 632971	MGIID:	3642998	Length:	204	Species:	Mus musculus

Alignment Length:	199	Identity:	73/199 - (36%)
Similarity:	107/199 - (53%)	Gaps:	20/199 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 ELKIAVIGAPSVGKSALIVRFLTKRYIGEYDHQTENRYKHEAMVDGEPVLFEILDTCPKAEDEYP 79
            |:|:||:|....|||||.|||||||:||||....|:.|.....::|:|:..||.|.|.:.:....
Mouse     3 EVKLAVLGGKGTGKSALTVRFLTKRFIGEYASNFESVYNKHLCLEGKPLNLEIYDPCSQPQKAKC 67

  Fly    80 NAAELVQWADGLLLVYSITDRKSFNY----IRRAKSDLQS------DTPVQLCANKVDMVHLRQV 134
            :....:.||||.|:||.|::|.||.:    |.|.:....:      :..|.|..||.|:.|:|:|
Mouse    68 SLTSELHWADGFLIVYDISNRPSFAFAQALIYRIREPPTTHCKRVVEPAVVLVGNKQDLCHMREV 132

  Fly   135 SRDEGEILAKDFECKFSEVSAADHVDQVAEVFNELCKEVL----------ASKRKSKQSLLERML 189
            ..:||:.||.||.|:|.|:|||:...:|..:|..|.|::|          .|..||...|:..:.
Mouse   133 GWEEGQKLAIDFRCQFCELSAAEQSLEVEVMFLRLIKDILMIFKHKEKRRPSGSKSMAKLINNVF 197

  Fly   190 GGAR 193
            |..|
Mouse   198 GKRR 201

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8519	NP_648054.2	small_GTPase	14..173	CDD:197466	66/167 (40%)
CG8519	NP_648054.2	P-loop_NTPase	17..173	CDD:304359	65/165 (39%)
Rergl	NP_001121562.1	small_GTPase	3..171	CDD:197466	66/167 (40%)
Rergl	NP_001121562.1	RERG_RasL11_like	5..171	CDD:206713	65/165 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0395
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1384728at2759
OrthoFinder	1	1.000	-	-		FOG0004892
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45704
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.920