Protein Alignment CG8519 and RIT1

DIOPT Version :10

• Sequence 1: NP_648054.2
• Gene: CG8519 / 38745
• FlyBaseID: FBgn0035711
• Length: 207
• Species: Drosophila melanogaster
• Sequence 2: NP_001243750.1
• Gene: RIT1 / 6016
• HGNCID: 10023
• Length: 236
• Species: Homo sapiens
• Alignment Length: 210
• Identity: 80/210 - (38%)
• Similarity: 119/210 - (56%)
• Gaps: 35/210 - (16%)

  Fly    15 ELKIAVIGAPSVGKSALIVRFLTKRYIGEYDHQTENRYKHEAMVDGEPVLFEILDTCPKAE---- 75
            |.|:.::||..|||||:.::|::.|:..::|...|:.||....:|.||...:||||..:||
Human    38 EYKLVMLGAGGVGKSAMTMQFISHRFPEDHDPTIEDAYKIRIRIDDEPANLDILDTAGQAEFTAM 102

  Fly    76 -DEYPNAAELVQWADGLLLVYSITDRKSFNYIRRAKSDL-----QSDTPVQLCANKVDMVHLRQV 134
             |:|..|.|      |.::.||||||:||:.:|..|..:     ..||||.|..||.|:..||||
Human   103 RDQYMRAGE------GFIICYSITDRRSFHEVREFKQLIYRVRRTDDTPVVLVGNKSDLKQLRQV 161

  Fly   135 SRDEGEILAKDFECKFSEVSAA--DHVDQVAEVFNELCKE--------VLASKRKS--KQSLLER 187
            :::||..||::|.|.|.|.|||  .::|   :||:.|.:|        |||.::||  |.|:.:|
Human   162 TKEEGLALAREFSCPFFETSAAYRYYID---DVFHALVREIRRKEKEAVLAMEKKSKPKNSVWKR 223

  Fly   188 MLGGARPYSRGKSDS 202
            :   ..|: |.|.||
Human   224 L---KSPF-RKKKDS 234

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8519	NP_648054.2	P-loop containing Nucleoside Triphosphate Hydrolases	17..173	CDD:476819	66/175 (38%)
RIT1	NP_001243750.1	Rit_Rin_Ric	37..208	CDD:206712	67/178 (38%)