DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8519 and rasl11b

DIOPT Version :9

Sequence 1:	NP_648054.2	Gene:	CG8519 / 38745	FlyBaseID:	FBgn0035711	Length:	207	Species:	Drosophila melanogaster
Sequence 2:	NP_956434.1	Gene:	rasl11b / 393109	ZFINID:	ZDB-GENE-040426-793	Length:	244	Species:	Danio rerio

Alignment Length:	182	Identity:	76/182 - (41%)
Similarity:	106/182 - (58%)	Gaps:	24/182 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 CKKSTLTELKIAVIGAPSVGKSALIVRFLTKRYIGEYDHQTENRYKHEAMVDGEPVLFEILDTCP 72
            |..|.:  :||||||...|||:||:|||||||:||:|:....|.|..|..:|||.|..::.|| |
Zfish    18 CPSSRV--IKIAVIGGSGVGKTALVVRFLTKRFIGDYERNVGNLYSREVQIDGEQVAIQVQDT-P 79

  Fly    73 KAEDEYPNAAEL---------VQWADGLLLVYSITDRKSFNYI-------RRAKSDLQSDTPVQL 121
            ..:   .||..|         :||||.:::|||:||||||:.|       .|..||  ...|:.|
Zfish    80 GVQ---VNANGLSCTDHVSRSIQWADAVVMVYSVTDRKSFDLIGQLHQLVTRTHSD--RSIPIIL 139

  Fly   122 CANKVDMVHLRQVSRDEGEILAKDFECKFSEVSAADHVDQVAEVFNELCKEV 173
            .|||.|::|:|:|...||.:|:....|.|.||||::..:||...|:.||.::
Zfish   140 VANKADLLHVRRVDAQEGPVLSSALSCSFYEVSASEDYNQVHSAFHRLCVDL 191

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8519	NP_648054.2	small_GTPase	14..173	CDD:197466	74/174 (43%)
CG8519	NP_648054.2	P-loop_NTPase	17..173	CDD:304359	74/171 (43%)
rasl11b	NP_956434.1	Small GTPase-like	19..242		75/181 (41%)
		small_GTPase	22..187	CDD:197466	72/172 (42%)
		RERG_RasL11_like	25..193	CDD:206713	74/173 (43%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	200..222
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	131	1.000	Domainoid score	I5114
eggNOG	1	0.900	-	-		E2759_KOG0395
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	132	1.000	Inparanoid score	I4596
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1384728at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm25211
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45704
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2264
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	10	9.930