Protein Alignment CG8519 and HRAS

DIOPT Version :10

• Sequence 1: NP_648054.2
• Gene: CG8519 / 38745
• FlyBaseID: FBgn0035711
• Length: 207
• Species: Drosophila melanogaster
• Sequence 2: NP_005334.1
• Gene: HRAS / 3265
• HGNCID: 5173
• Length: 189
• Species: Homo sapiens
• Alignment Length: 175
• Identity: 55/175 - (31%)
• Similarity: 88/175 - (50%)
• Gaps: 18/175 - (10%)

  Fly    13 LTELKIAVIGAPSVGKSALIVRFLTKRYIGEYDHQTENRYKHEAMVDGEPVLFEILDTCPKAE-- 75
            :||.|:.|:||..||||||.::.:...::.|||...|:.|:.:.::|||..|.:||||..:.|
Human     1 MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYS 65

  Fly    76 ---DEYPNAAELVQWADGLLLVYSITDRKSFNYIRRAKSDLQ-----SDTPVQLCANKVDMVHLR 132
               |:|....|      |.|.|::|.:.|||..|.:.:..::     .|.|:.|..||.|:. .|
Human    66 AMRDQYMRTGE------GFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDLA-AR 123

  Fly   133 QVSRDEGEILAKDFECKFSEVSAADHVDQVAEVFNELCKEVLASK 177
            .|...:.:.||:.:...:.|.||... ..|.:.|..|.:|:...|
Human   124 TVESRQAQDLARSYGIPYIETSAKTR-QGVEDAFYTLVREIRQHK 167

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8519	NP_648054.2	P-loop containing Nucleoside Triphosphate Hydrolases	17..173	CDD:476819	51/165 (31%)
HRAS	NP_005334.1	H_N_K_Ras_like	3..164	CDD:133338	53/168 (32%)
		Effector region	32..40		3/7 (43%)
		Hypervariable region	166..185		1/2 (50%)