DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8519 and rergl

DIOPT Version :9

Sequence 1:	NP_648054.2	Gene:	CG8519 / 38745	FlyBaseID:	FBgn0035711	Length:	207	Species:	Drosophila melanogaster
Sequence 2:	XP_017947954.1	Gene:	rergl / 100491594	XenbaseID:	XB-GENE-6037390	Length:	235	Species:	Xenopus tropicalis

Alignment Length:	205	Identity:	84/205 - (40%)
Similarity:	119/205 - (58%)	Gaps:	22/205 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 ELKIAVIGAPSVGKSALIVRFLTKRYIGEYDHQTENRYKHEAMVDGEPVLFEILDTCPKAEDEYP 79
            |..|.|:||..||||||.|||||:|:||||. :.|:.|.|...|||:.|:|.|.| .|.|:|...
Frog    35 EANILVLGADGVGKSALTVRFLTRRFIGEYG-ELESIYSHNVCVDGKEVIFNIWD-FPYAKDPTE 97

  Fly    80 NAA----ELVQWADGLLLVYSITDRKSFN-------YIRRAKSDLQSD-TPVQLCANKVDMVHLR 132
            .:.    :.:|||||.:|||||.||.|||       .|:.||..|.:: .|:.:..||.|:.|||
Frog    98 ESCAEEEKRMQWADGYVLVYSICDRASFNVMCQTIQLIKTAKDCLGAEKLPIVIVGNKRDLHHLR 162

  Fly   133 QVSRDEGEILAKDFECKFSEVSAADHVDQVAEVFNELCKEVLASKRKSK-----QSLLERMLGGA 192
            .||.:||.:||...:|.|.|||||:....|..||:.|..::..||..:|     :.:::.|   :
Frog   163 AVSSEEGRLLALSMDCDFYEVSAAEAYHGVLMVFHGLVDKIRESKLVTKKGTGIRGIVKSM---S 224

  Fly   193 RPYSRGKSDS 202
            ..::|.::||
Frog   225 AVFARRRTDS 234

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8519	NP_648054.2	small_GTPase	14..173	CDD:197466	77/169 (46%)
CG8519	NP_648054.2	P-loop_NTPase	17..173	CDD:304359	76/167 (46%)
rergl	XP_017947954.1	P-loop_NTPase	37..205	CDD:393306	76/169 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1384728at2759
OrthoFinder	1	1.000	-	-		FOG0004892
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45704
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.020