DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SP1173 and MFSD6L

DIOPT Version :9

Sequence 1:	NP_648053.1	Gene:	SP1173 / 38744	FlyBaseID:	FBgn0035710	Length:	741	Species:	Drosophila melanogaster
Sequence 2:	NP_689812.3	Gene:	MFSD6L / 162387	HGNCID:	26656	Length:	586	Species:	Homo sapiens

Alignment Length:	283	Identity:	49/283 - (17%)
Similarity:	90/283 - (31%)	Gaps:	111/283 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly   412 YVW-------GAIGYVVLFSPLDLFFFQNEPNHDAALVALIIFIVSFVLGAVVLLCATQMPLSPP 469
            :||       |..|...|...||.|...:.|.      .::.|....|:..:.||.:...|:...
Human   288 WVWRLLGMSAGVCGITALVGQLDCFLMTSGPR------GVVHFYGYSVVSTLALLVSIAFPIPIC 346

  Fly   470 EWWWHTKTGMLVVPMSAIRRYTPEILVLTLVSILFGTFWSSIHSYLWWTFTD------------- 521
            :.|   :.....|...:|....|.:::|...::|.|...|::.::|:|...|
Human   347 QQW---EPSYKRVKALSIVGGDPHLILLASTTVLVGAIVSTVQNFLFWHMKDHGSGELVMGFSVA 408

  Fly   522 ---------------------------VDAVCYSGLIL---------------IL------VLFF 538
                                       :...|.:|.:|               ||      .|::
Human   409 LSLLGEILLHPFKATLLRKLSRTGLVGLGLSCLAGQLLYYSFLWSWWSVLPIQILSAISNRALWW 473

  Fly   539 NVDKFIE--------------YCGH-------SNIFIGGLAIFVIRFTALSDAQTKWLTVIMETI 582
            .|...:|              :.||       ...|:||..  |:||:         |.|:.:..
Human   474 AVGASVEDLATPRMERALSALFRGHFYGSGCSLGSFVGGFV--VMRFS---------LAVLYQAC 527

  Fly   583 EPAVIGLIWITIILYMRHAMPRK 605
              .|..|:|:.::|.::..:||:
Human   528 --CVALLLWLALLLSIQRRLPRE 548

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SP1173	NP_648053.1	MFS	15..88	CDD:304372
SP1173	NP_648053.1	Chromate_transp	<552..632	CDD:302665	14/54 (26%)
MFSD6L	NP_689812.3	MFS	<28..87	CDD:304372
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	133..160
		MFS	368..>529	CDD:119392	25/173 (14%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165157828
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3762
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR16172
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.840