Protein Alignment SP1173 and Sugb

DIOPT Version :10

• Sequence 1: NP_648053.1
• Gene: SP1173 / 38744
• FlyBaseID: FBgn0035710
• Length: 741
• Species: Drosophila melanogaster
• Sequence 2: XP_314086.5
• Gene: Sugb / 1274895
• VectorBaseID: AGAMI1_012660
• Length: 675
• Species: Anopheles gambiae
• Alignment Length: 791
• Identity: 163/791 - (20%)
• Similarity: 268/791 - (33%)
• Gaps: 254/791 - (32%)

  Fly    11 VNKTLISLKFVVFFVITGLTALHVLHATKPLLLGLNFSEYRTITILAPFVSILGPLIAGPWADRL 75
            :||.|:.:|...|....|...:.....|....||.:.....||..:.|.|.:|...:.|..|||.
Mosquito     4 INKKLLPMKAHYFLFNAGTAPVVPFMPTLVRQLGFSTVIVGTIYTVLPIVGMLVKPLFGIIADRF 68

  Fly    76 AAKNPNTFGKTLRVLTAVFLLISA---FIYAFLFAVPEVTRRGEIREPLVSFGCDETGGFLFQER 137
            ..:         ::|..:|.:::|   |:..|:.|:|:        :..|:|.|......|  :.
Mosquito    69 QRQ---------KLLFLIFQILTAVPFFLIMFIPAIPQ--------DSTVTFHCHNGAADL--KY 114

  Fly   138 CGSNAT----CSRWDQKEGKINLT-RCTYSCQNPKLYEPLYVAWLAEVPTVAPSTEQSSEFDYED 197
            |..|.|    |........:.|.| .|...|:.    ||    |:.:  ||......|:..|
Mosquito   115 CPDNGTSIDACLVESITTNESNGTLLCDMECRT----EP----WMWD--TVCKYWNVSAYCD--- 166

  Fly   198 EGSTAVTESLRTRRDVESSDPADSAGVEAISGEVPLHRSIRQVKKPPTKVYVQPPHVC----LTE 258
                            |.:.|||.  :..::|.|| :..|..|.:            |    |.|
Mosquito   167 ----------------EKNIPADR--ILRLTGVVP-NNHINLVDE------------CLYFMLRE 200

  Fly   259 RNQNGEDVVKHCHAYTEDTTSVVMDALMGSAISQEEHYDDYEGWCQYPLEGFQCHIPEEQVNYMK 323
            ...:|..|..:|.|.|                      .|:...||     .||:  .|||  |.
Mosquito   201 GQMDGGRVPLYCPANT----------------------TDFRTSCQ-----VQCN--NEQV--MG 234

  Fly   324 DFKHYMQNDSNCKPMIECQVVNPYHEQSVLSDSECTNTTGSVQDTLVGYTTIRLIGDIFPMAALT 388
            ...|                       |.::|.:   .||..|..|           :|....::
Mosquito   235 AISH-----------------------SKIADGD---VTGLYQFWL-----------LFLFLIVS 262

  Fly   389 LLNTAIVIAVRETSEGRGEVC------------RQYVWGAIGY--VVLFSPLDLFFFQNEPNHDA 439
            ....|:|::|.:.      :|            .|.:||:||:  |.||:.     |..:...:.
Mosquito   263 WAGMAVVVSVGDA------ICFEMLGDKPHLYGNQRLWGSIGWGTVSLFAG-----FLVDTLSEG 316

  Fly   440 ALVA--LIIFIVSFVLGAVVLLCATQMPLSPPEWWWHTKTGMLVVPMSAIRRYTPEILVLTL--- 499
            .|..  .|:|.::.||....:||::::.        ||:|.:....:..:.:......:...
Mosquito   317 KLTKDYTIVFYMTIVLIGFDMLCSSKLQ--------HTQTRLSTNILKDVGKIFVNFRICVFFCW 373

  Fly   500 -VSILFGTFWSSIHSYLWWTFTDVDAV---C--------YSGLILI-------LVLFFNVDKFIE 545
             |.|.|||  :.|.::|:|...|:.:.   |        ..|:|:.       |..||.....::
Mosquito   374 CVLIGFGT--ALIWNFLFWHLEDLASAQEGCGHSTWIKTLEGIIMSIQTFGGELPFFFLSGWILK 436

  Fly   546 YCGH----SNIFIGGLAIFVIRFTALSDAQTKWLTVIMETIEPAVIGLIWITIILYMRHAMPRKL 606
            ..||    |.:.:|    |.:||...|.....|..:.:|.:.....||.:.|:..|.....|...
Mosquito   437 KIGHIHAMSLVLLG----FGVRFLLYSLLTDPWWVIPIEFMNGITFGLFYATMASYASIVAPPGT 497

  Fly   607 TATGQAIAVLAFFGLGKGFGAL--------IGLARDERDPKLEFWSCTYQWLAIVACVVALIYFG 663
            .||.|.:....|.|:|...|:|        ||            .|.|::...    ..|||.|.
Mosquito   498 EATMQGLVGAVFEGVGVSLGSLLAGNLFHRIG------------GSATFRAFG----TAALILFV 546

  Fly   664 IYNLI--LAPRCTAKPQHSEELISGSASQNFGNTGNGNGAGNGTGNGNGAGASLNGNGNGSYSPL 726
            ::.::  |..|.:::.:..::.::|........        |||..|:|.|...||..||
Mosquito   547 LHVVVQKLTDRFSSQGKQKQQKMNGLTDVKLKE--------NGTHCGSGGGLGENGLSNG----- 598

  Fly   727 RVYHNERGKKG 737
                 :.||.|
Mosquito   599 -----QLGKTG 604

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SP1173	NP_648053.1	MFS	15..>112	CDD:475125	23/99 (23%)
		MFS	<368..630	CDD:475125	63/311 (20%)
Sugb	XP_314086.5	None