Protein Alignment SP1173 and jef

DIOPT Version :10

• Sequence 1: NP_648053.1
• Gene: SP1173 / 38744
• FlyBaseID: FBgn0035710
• Length: 741
• Species: Drosophila melanogaster
• Sequence 2: XP_312908.4
• Gene: jef / 1273877
• VectorBaseID: AGAMI1_006530
• Length: 722
• Species: Anopheles gambiae
• Alignment Length: 820
• Identity: 147/820 - (17%)
• Similarity: 245/820 - (29%)
• Gaps: 292/820 - (35%)

  Fly    11 VNKTLISLKFVVFFVITGLTALHVLHATKPLLLGLNFSEYRTITILAPFVSILGPLIAGPWADRL 75
            |::.|:.:|...||..:...:|..|.......:|:|..:...:....|||..|.....|.:|||.
Mosquito    76 VDQELLPVKTFYFFFYSAFGSLFPLMGVYFKQMGMNPGQCGLLIGTRPFVEFLSAPFWGSYADRC 140

  Fly    76 AAKNPNTFGKTLRVLTAVFLLISAFIYAFLFAVPEVTRRGEIREPLVSFGCDETGGFLFQERCGS 140
            ..      ||        .||:::.....:|.:|    .|.|:.|..|  |.|.          .
Mosquito   141 KK------GK--------MLLLASLAAWIIFTLP----LGFIQPPATS--CIER----------K 175

  Fly   141 NATCSRWDQKEGKINLTRCTYSCQNPKLYEPLYVAWLAEVPTVAPSTEQSSEFDYEDEGSTAVTE 205
            |||                .:..:.|            :||.:...:...|..:....|..|...
Mosquito   176 NAT----------------DFELRTP------------QVPRILKRSIDESMLEELSFGKYATDS 212

  Fly   206 SLRTRRDVESSDPADSAGVEAISGEVPLHRSIRQVKKPPTKVYVQPPHVCLTERNQNGEDVVKHC 270
            .....|...::.|..:|||.
Mosquito   213 GSSFTRVERAARPVAAAGVS--------------------------------------------- 232

  Fly   271 HAYTEDTTSVVMDALMGSAISQEEHYDDYEGWCQYPLEGFQCHIPEEQVNYMKDFKHYMQNDSNC 335
                                               ||:          |:|..:|...:..|
Mosquito   233 -----------------------------------PLD----------VSYANNFNEKLHRD--- 249

  Fly   336 KPMIECQVVNPYHEQSVLSDSECTNTTGSVQDTLVGYTTIRLIGDIFPMAALTLLNTAIVIAVRE 400
                   .|:|..       |.....|..:|........:.:||:.|...|:||.::|::..:.|
Mosquito   250 -------WVSPLF-------SSIVYRTADIQKAFFLLLLLVIIGEFFSAPAITLADSAVITILGE 300

  Fly   401 TSEGRGEVCRQYVWGAIGYVVLFSPLDLFFFQNEPNHDAALV------------ALIIFIVSFVL 453
            .::..|   .|.::|::|:     .|.:||.....:|..|..            ..|.|....||
Mosquito   301 DADRYG---HQRMFGSLGW-----GLAMFFVGIALDHSTAFPDHPCGPEKQEKNYTICFATFSVL 357

  Fly   454 GAVVLLCATQM--------PLSP------PEWWWH-------------------TKTGM--LVVP 483
            ....|:.|||:        |..|      |:...|                   |.|||  ...|
Mosquito   358 MGAALISATQIQFKYDYSEPQEPVQVEKVPQELTHEEQMQAQLAQQLQLPSLAATGTGMASAAPP 422

  Fly   484 MSAI----------RRYTPEILV-------LTLVSILFGTFWSS-----IHSYLWWTFTDVDAVC 526
            .:|:          .|..||.:.       |...|.||..::..     |.::|:|...|
Mosquito   423 PAALGAQTKMFAQTTREMPEWVTVLKQFKNLKCASFLFVAWFMGFGIGLIFTFLFWHLQD----- 482

  Fly   527 YSG-------------LILILVLFFNVDKFIEYCGHSNIFIGGLAIFVIRFTALSDAQTKWLTVI 578
            |.|             :..|...||:. :.|...||..:...||...::||..:|..:..|..:.
Mosquito   483 YGGSPTLFGVASVINHISEIFAYFFSF-RLITQIGHVKVLCLGLVGNILRFLYISYLKNPWWVLP 546

  Fly   579 METIEPAVIGLIWITIILYMRHAMPRKLTATGQAIAVLAFFGLGKGFGALIGLARDERDPKLEFW 643
            .|.::......:|.....|:.|..|:.|.::.|.:......|||:|.||:||      ...:.::
Mosquito   547 FEFMQGITHAAVWAACCSYIAHNTPQHLRSSAQGVLQGLHHGLGRGCGAVIG------GMFVTYF 605

  Fly   644 --SCTYQWLAIVACVVALIYFGIYNL------ILAPRCTAKPQH---------------SEELIS 685
              :.|::...:: |::.|..|...|.      .::...|.:..|               |..:..
Mosquito   606 GTTATFRGYGVI-CILVLAAFVFINFYRKDEGFISEIPTTEDPHQVAEETAHLAPHGVPSNPIPR 669

  Fly   686 GSASQNFGNTGNGNGAGNGTGNGNGAGASLNGNGNGSYSP 725
            ..:|......|..| ..||.|.....|.:|:..|....:|
Mosquito   670 ALSSTRLNEIGQQN-VDNGYGTYQTTGGALDVPGGAPKNP 708

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SP1173	NP_648053.1	MFS	15..>112	CDD:475125	22/96 (23%)
		MFS	<368..630	CDD:475125	73/343 (21%)
jef	XP_312908.4	MFS_MFSD6	82..630	CDD:340893	131/733 (18%)