Protein Alignment eIF4E4 and CDC33

DIOPT Version :9

• Sequence 1: NP_648052.1
• Gene: eIF4E4 / 38743
• FlyBaseID: FBgn0035709
• Length: 229
• Species: Drosophila melanogaster
• Sequence 2: NP_014502.1
• Gene: CDC33 / 854026
• SGDID: S000005499
• Length: 213
• Species: Saccharomyces cerevisiae
• Alignment Length: 179
• Identity: 67/179 - (37%)
• Similarity: 106/179 - (59%)
• Gaps: 16/179 - (8%)

  Fly    41 PVTEIVD---LRLKHPLENTWTLWYLEN--DRSKNWEDMQNEITSFDMVEDFWSLYNHIKQPSEI 100
            |.|.:.|   ..:||||...|||||.:.  |:|::|.|:...:|||..||:||::..:|.:|.|:
Yeast    23 PKTVLSDSAHFDVKHPLNTKWTLWYTKPAVDKSESWSDLLRPVTSFQTVEEFWAIIQNIPEPHEL 87

  Fly   101 RVGSDYSLFKKGIQPMWEDDANKFGGRWVINMGRGSKAELDKLWLDVLLILIGEAF-ENTEEVCG 164
            .:.|||.:|:..::|.|||:||..||:|...: ||..|::|:|||..||.:|||.. |:..::.|
Yeast    88 PLKSDYHVFRNDVRPEWEDEANAKGGKWSFQL-RGKGADIDELWLRTLLAVIGETIDEDDSQING 151

  Fly   165 AVINLRGKSNKISIWTANGHNELAVMEIGLKLRDLLVLP--------PH 205
            .|:::|...||.::||.:...| .::.||.|.:.:|.|.        ||
Yeast   152 VVLSIRKGGNKFALWTKSEDKE-PLLRIGGKFKQVLKLTDDGHLEFFPH 199

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF4E4	NP_648052.1	IF4E	56..209	CDD:279921	60/161 (37%)
CDC33	NP_014502.1	CDC33	1..213	CDD:227386	67/179 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157346522
Domainoid	1	1.000	139	1.000	Domainoid score	I1034
eggNOG	1	0.900	-	-		E1_COG5053
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	146	1.000	Inparanoid score	I1143
Isobase	1	0.950	-	0	Normalized mean entropy	S964
OMA	1	1.010	-	-		QHG54586
OrthoFinder	1	1.000	-	-		FOG0000666
OrthoInspector	1	1.000	-	-		otm46506
orthoMCL	1	0.900	-	-		OOG6_100627
Panther	1	1.100	-	-	O	PTHR11960
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R595
SonicParanoid	1	1.000	-	-		X406
TreeFam	1	0.960	-	-
	15	14.740