back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment eIF4E4 and eif4ea

DIOPT Version :9

Sequence 1:	NP_648052.1	Gene:	eIF4E4 / 38743	FlyBaseID:	FBgn0035709	Length:	229	Species:	Drosophila melanogaster
Sequence 2:	NP_571808.1	Gene:	eif4ea / 79380	ZFINID:	ZDB-GENE-040413-1	Length:	215	Species:	Danio rerio

Alignment Length:	211	Identity:	95/211 - (45%)
Similarity:	140/211 - (66%)	Gaps:	9/211 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 SPSSSSEDLKTLSDMDIRKPVTEIVDLRLKHPLENTWTLWYLENDRSKNWEDMQNEITSFDMVED 86
            :||:|.|     .:.:..:.:..:.|. :||||:|.|.||:.:||:||.|:.....|:.||.|||
Zfish    11 NPSNSEE-----KNEENEQQIVSLEDY-IKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVED 69

  Fly    87 FWSLYNHIKQPSEIRVGSDYSLFKKGIQPMWEDDANKFGGRWVINMGRGS-KAELDKLWLDVLLI 150
            ||:|||||:..|.:..|.||||||.||:|||||:.||.||||:|.:.:.. :|:||:.||:.||.
Zfish    70 FWALYNHIQLSSNLMSGCDYSLFKDGIEPMWEDERNKRGGRWLITLSKQQRRADLDRFWLETLLC 134

  Fly   151 LIGEAF-ENTEEVCGAVINLRGKSNKISIWTANGHNELAVMEIGLKLRDLLVLPPHQ-LQYQLHK 213
            |:|||| :::::|||||:|:|.|.:||:|||.:..|:.|::.||...::.|.:||.. :.||.|.
Zfish   135 LVGEAFDDHSDDVCGAVVNIRTKGDKIAIWTTDYENKDAIVHIGRVYKERLGVPPKVIIGYQSHA 199

  Fly   214 DTMCKQGSVIKAVYCV 229
            ||..|.||..|..:.|
Zfish   200 DTATKSGSTTKNKFVV 215

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.