DRSC/TRiP Functional Genomics Resources

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Protein Alignment eIF4E4 and Eif4e1b

DIOPT Version :9

Sequence 1:NP_648052.1 Gene:eIF4E4 / 38743 FlyBaseID:FBgn0035709 Length:229 Species:Drosophila melanogaster
Sequence 2:XP_038952114.1 Gene:Eif4e1b / 686104 RGDID:1585494 Length:263 Species:Rattus norvegicus


Alignment Length:232 Identity:96/232 - (41%)
Similarity:143/232 - (61%) Gaps:9/232 - (3%)


- Green bases have known domain annotations that are detailed below.


  Fly     5 QQTEFKMMDNGTETLADSPSSSSED----LKTLSDMDIRKPVTEIVDLRLKHPLENTWTLWYLEN 65
            ::.|.::.:..:|..|:.....:.|    |||:.....|:..|::.  |..|||:..|.||:.:|
  Rat    34 EEEEEEVKEKPSEATAEGLQGEARDLPGSLKTVKQKAQREHPTKLP--RELHPLQFRWVLWFFKN 96

  Fly    66 DRSKNWEDMQNEITSFDMVEDFWSLYNHIKQPSEIRVGSDYSLFKKGIQPMWEDDANKFGGRWVI 130
            |||:.|:|....:|.||.|||||:.|.|:|..|::..|.||:|||:||||||||..||.||||::
  Rat    97 DRSRAWQDNLQLVTKFDTVEDFWATYRHVKLASKLSCGCDYALFKEGIQPMWEDSRNKRGGRWLL 161

  Fly   131 NMGRGSK-AELDKLWLDVLLILIGEAFEN-TEEVCGAVINLRGKSNKISIWTANGHNELAVMEIG 193
            ::.:..: .|||:|||:.||.|:||:||. :.||||||:|:|.|.:||::||:...|:..||.||
  Rat   162 SLAKQQRHMELDRLWLETLLCLLGESFEEYSGEVCGAVVNIRTKGDKIALWTSEAENKAGVMHIG 226

  Fly   194 LKLRDLLVLPPHQ-LQYQLHKDTMCKQGSVIKAVYCV 229
            ...::.|.|.... :.||.|.||..|..|:.|..:.|
  Rat   227 HIYKERLGLSTKTIIGYQAHADTAAKSNSLAKNKFVV 263

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
eIF4E4NP_648052.1 IF4E 56..209 CDD:279921 74/155 (48%)
Eif4e1bXP_038952114.1 IF4E 84..243 CDD:396291 76/158 (48%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1394271at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.010

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