Protein Alignment eIF4E4 and eif4e2

DIOPT Version :10

• Sequence 1: NP_648052.1
• Gene: eIF4E4 / 38743
• FlyBaseID: FBgn0035709
• Length: 229
• Species: Drosophila melanogaster
• Sequence 2: NP_001005099.1
• Gene: eif4e2 / 448677
• XenbaseID: XB-GENE-5823950
• Length: 234
• Species: Xenopus tropicalis
• Alignment Length: 224
• Identity: 75/224 - (33%)
• Similarity: 123/224 - (54%)
• Gaps: 22/224 - (9%)

  Fly    12 MDNGTETLADSPS---SSSEDLKTLSDMDIRKPVTE----------IVDLRLKHPLENTWTLWYL 63
            |:|..:.|.|..|   ..:|:..|..|.:..|...|          :|....:|||:..:|.||.
 Frog     1 MNNKFDALKDDDSGDHDQNEENGTQKDSEKEKNEKEKNQGSSRKKSVVPGPAEHPLQYNYTFWYS 65

  Fly    64 EN-----DRSKNWEDMQNEITSFDMVEDFWSLYNHIKQPSEIRVGSDYSLFKKGIQPMWEDDANK 123
            ..     ..|:::|....:|.:|..||.||..|:|:.:|.::...||:.|||:||:|||||||||
 Frog    66 RRTPGRPTSSQSYEQNIKQIGTFASVEQFWRFYSHMVRPGDLTGHSDFHLFKEGIKPMWEDDANK 130

  Fly   124 FGGRWVINMGRGSKAELDKLWLDVLLILIGEAFENTEEVCGAVINLRGKSNKISIWTANGHNELA 188
            .||:|:|.:.:|..:   :.|.:::|.::||.|...||:||||:::|.:.:.||||.....::..
 Frog   131 NGGKWIIRLRKGLAS---RCWENLILAMLGEQFMVGEEICGAVVSVRFQEDIISIWNKTASDQAT 192

  Fly   189 VMEIGLKLRDLLVLPPHQ-LQYQLHKDTM 216
            ...|...||.:|.|||:. ::|:.|.|::
 Frog   193 TARIRDTLRRVLNLPPNTVMEYKTHTDSI 221

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF4E4	NP_648052.1	IF4E	53..209	CDD:460281	60/161 (37%)
eif4e2	NP_001005099.1	IF4E	55..214	CDD:460281	60/161 (37%)