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Protein Alignment eIF4E4 and eif4e3

DIOPT Version :9

Sequence 1:	NP_648052.1	Gene:	eIF4E4 / 38743	FlyBaseID:	FBgn0035709	Length:	229	Species:	Drosophila melanogaster
Sequence 2:	NP_001004589.1	Gene:	eif4e3 / 447850	ZFINID:	ZDB-GENE-040912-156	Length:	224	Species:	Danio rerio

Alignment Length:	205	Identity:	54/205 - (26%)
Similarity:	96/205 - (46%)	Gaps:	30/205 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 SPSSSSEDLKTLSDMDIRKPVTEIVDLRLKHPLENTWTLWYLENDRS------KNWEDMQNEITS 80
            ||.:|:|:...:.:.::.. :|..|:.....||.:.||.|.   |||      ...|....:|.:
Zfish    18 SPVNSTENDIHIDERELEN-ITNHVEDGTSLPLHSPWTFWL---DRSLPGTTAAECESNLKKIYT 78

  Fly    81 FDMVEDFWSLYNHIKQPSEIRVGSDYSLFKKGIQPMWEDDANKFGGRWVINMGRGSKAELDKLWL 145
            ...|:.|||:||:|...|.:.:...|.|.:...:|:||:::|..||.|.:.:.:.|..   .:|.
Zfish    79 VHTVQSFWSVYNNIPPVSCLPLRCSYHLMRGERRPLWEEESNAKGGVWKMKVPKESTL---AVWK 140

  Fly   146 DVLLILIGEAF----ENTEEVCGAVINLRGKSNKISIWTANGH--NELAVM--------EIGLKL 196
            ::||..|||.|    .:.:||.|..:::|.:.:.:.:|..|..  ||..|:        :|..|
Zfish   141 ELLLATIGEQFTDYCASEDEVVGVSVSVREREDVVQVWNGNASFANEANVLGRIYELLPQISFK- 204

  Fly   197 RDLLVLPPHQ 206
              .:...||:
Zfish   205 --AVFYKPHE 212

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.