Protein Alignment eIF4E4 and eif4e2rs1

DIOPT Version :10

• Sequence 1: NP_648052.1
• Gene: eIF4E4 / 38743
• FlyBaseID: FBgn0035709
• Length: 229
• Species: Drosophila melanogaster
• Sequence 2: NP_957053.1
• Gene: eif4e2rs1 / 393732
• ZFINID: ZDB-GENE-040426-1728
• Length: 228
• Species: Danio rerio
• Alignment Length: 220
• Identity: 69/220 - (31%)
• Similarity: 121/220 - (55%)
• Gaps: 23/220 - (10%)

  Fly    14 NGTETLADSPSSSSEDLKTLSDMD-----------IRKPVTEIVDLRLKHPLENTWTLWYLENDR 67
            |..|.|.:......|::|..::.|           .||.||....   :|||:..:|.||.....
Zfish     2 NQFEHLKEEDCGDHEEMKDNNESDRASINNNNNNIRRKMVTPAAG---EHPLQYNYTFWYSRRTP 63

  Fly    68 SK-----NWEDMQNEITSFDMVEDFWSLYNHIKQPSEIRVGSDYSLFKKGIQPMWEDDANKFGGR 127
            |:     ::|....::.:...||.||..|:|:.:|.::...||:.|||:||:|||||:|||.||:
Zfish    64 SRPANTQSYEQNIRQMGTVASVEQFWKFYSHLVRPGDLTGHSDFHLFKEGIKPMWEDEANKNGGK 128

  Fly   128 WVINMGRGSKAELDKLWLDVLLILIGEAFENTEEVCGAVINLRGKSNKISIWTANGHNELAVMEI 192
            |:|.:.:|..:   :.|.:::|.::||.|...||:||.|:::|.:.:.:|||....::::....|
Zfish   129 WIIRLRKGLAS---RFWENIILAMLGEQFMVGEEICGVVVSIRFQEDILSIWNKTANDQVTTSRI 190

  Fly   193 GLKLRDLLVLPPHQ-LQYQLHKDTM 216
            ...||.:|.|||:. ::|:.|.|::
Zfish   191 RDTLRRVLNLPPNTIMEYKTHNDSL 215

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF4E4	NP_648052.1	IF4E	53..209	CDD:460281	55/161 (34%)
eif4e2rs1	NP_957053.1	IF4E	49..208	CDD:460281	55/161 (34%)