Protein Alignment eIF4E4 and Eif4e2

DIOPT Version :10

• Sequence 1: NP_648052.1
• Gene: eIF4E4 / 38743
• FlyBaseID: FBgn0035709
• Length: 229
• Species: Drosophila melanogaster
• Sequence 2: NP_001389132.1
• Gene: Eif4e2 / 363275
• RGDID: 1307790
• Length: 245
• Species: Rattus norvegicus
• Alignment Length: 228
• Identity: 75/228 - (32%)
• Similarity: 124/228 - (54%)
• Gaps: 22/228 - (9%)

  Fly    12 MDNGTETLADSPS---SSSEDLKTLSDMDIRKPVTE----------IVDLRLKHPLENTWTLWYL 63
            |:|..:.|.|..|   ..:|:..|..|.:..|...:          :|....:|||:..:|.||.
  Rat     1 MNNKFDALKDDDSGDHDQNEENSTQKDGEKEKTDRDKSQSGGKRKAVVPGPAEHPLQYNYTFWYS 65

  Fly    64 EN-----DRSKNWEDMQNEITSFDMVEDFWSLYNHIKQPSEIRVGSDYSLFKKGIQPMWEDDANK 123
            ..     ..|:::|....:|.:|..||.||..|:|:.:|.::...||:.|||:||:|||||||||
  Rat    66 RRTPGRPTSSQSYEQNIKQIGTFASVEQFWKFYSHMVRPGDLTGHSDFHLFKEGIKPMWEDDANK 130

  Fly   124 FGGRWVINMGRGSKAELDKLWLDVLLILIGEAFENTEEVCGAVINLRGKSNKISIWTANGHNELA 188
            .||:|:|.:.:|..:   :.|.:::|.::||.|...||:||||:::|.:.:.||||.....::..
  Rat   131 NGGKWIIRLRKGLAS---RCWENLILAMLGEQFMVGEEICGAVVSVRFQEDIISIWNKTASDQAT 192

  Fly   189 VMEIGLKLRDLLVLPPHQ-LQYQLHKDTMCKQG 220
            ...|...||.:|.|||:. ::|:.|.|::...|
  Rat   193 TARIRDTLRRVLNLPPNTIMEYKTHTDSIKMPG 225

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF4E4	NP_648052.1	IF4E	53..209	CDD:460281	60/161 (37%)
Eif4e2	NP_001389132.1	IF4E	55..214	CDD:460281	60/161 (37%)