Protein Alignment eIF4E4 and Eif4e3

DIOPT Version :9

• Sequence 1: NP_648052.1
• Gene: eIF4E4 / 38743
• FlyBaseID: FBgn0035709
• Length: 229
• Species: Drosophila melanogaster
• Sequence 2: NP_001100082.1
• Gene: Eif4e3 / 297481
• RGDID: 1586185
• Length: 207
• Species: Rattus norvegicus
• Alignment Length: 218
• Identity: 58/218 - (26%)
• Similarity: 102/218 - (46%)
• Gaps: 38/218 - (17%)

  Fly    20 ADSPSSSSEDL-KTLSDMDIRKPVTEIVDLRLKHPLENTWTLWYLENDRS------KNWEDMQNE 77
            |.:|..:||.| |.||.:   :|....:      ||.:.||.|.   |||      ........:
  Rat     6 AAAPPGASEPLGKALSAL---QPEPGSI------PLHSPWTFWL---DRSLPGATAAECASNLKK 58

  Fly    78 ITSFDMVEDFWSLYNHIKQPSEIRVGSDYSLFKKGIQPMWEDDANKFGGRWVINMGRGSKAELDK 142
            |.:...|:.|||:||:|...:.:.:...|.|.:...:|:||:::|..||.|.:.:.:.|.:   .
  Rat    59 IYTVQTVQIFWSVYNNIPPVTSLPLRCSYHLMRGERRPLWEEESNAKGGVWKMKVPKDSTS---T 120

  Fly   143 LWLDVLLILIGEAFEN----TEEVCGAVINLRGKSNKISIWTANGH--NELAVMEIGLKLRDLLV 201
            :|.::||..|||.|.:    .:|:.|..:::|.:.:.:.:|..|..  .|..|:|   |:..||
  Rat   121 VWKELLLATIGEQFTDCAAADDEIIGVSVSVRDREDVVQVWNVNASLVGEATVLE---KIHQLL- 181

  Fly   202 LPPH----QLQYQLHKDTMCKQG 220
              ||    .:.|:.|::....:|
  Rat   182 --PHISFKAVFYKPHEEHHAFEG 202

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF4E4	NP_648052.1	IF4E	56..209	CDD:279921	44/168 (26%)
Eif4e3	NP_001100082.1	IF4E	34..181	CDD:279921	40/155 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166334513
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5053
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1394271at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.750