Protein Alignment eIF4E4 and Eif4e2

DIOPT Version :10

• Sequence 1: NP_648052.1
• Gene: eIF4E4 / 38743
• FlyBaseID: FBgn0035709
• Length: 229
• Species: Drosophila melanogaster
• Sequence 2: XP_036021474.1
• Gene: Eif4e2 / 26987
• MGIID: 1914440
• Length: 265
• Species: Mus musculus
• Alignment Length: 224
• Identity: 74/224 - (33%)
• Similarity: 123/224 - (54%)
• Gaps: 22/224 - (9%)

  Fly    12 MDNGTETLADSPS---SSSEDLKTLSDMDIRKPVTE----------IVDLRLKHPLENTWTLWYL 63
            |:|..:.|.|..|   ..:|:..|..|.:..|...:          :|....:|||:..:|.||.
Mouse     1 MNNKFDALKDDDSGDHDQNEENSTQKDGEKEKTDRDKSQSSGKRKAVVPGPAEHPLQYNYTFWYS 65

  Fly    64 EN-----DRSKNWEDMQNEITSFDMVEDFWSLYNHIKQPSEIRVGSDYSLFKKGIQPMWEDDANK 123
            ..     ..|:::|....:|.:|..||.||..|:|:.:|.::...||:.|||:||:|||||||||
Mouse    66 RRTPGRPTSSQSYEQNIKQIGTFASVEQFWKFYSHMVRPGDLTGHSDFHLFKEGIKPMWEDDANK 130

  Fly   124 FGGRWVINMGRGSKAELDKLWLDVLLILIGEAFENTEEVCGAVINLRGKSNKISIWTANGHNELA 188
            .||:|:|.:.:|..:   :.|.:::|.::||.|...||:||||:::|.:.:.||||.....::..
Mouse   131 NGGKWIIRLRKGLAS---RCWENLILAMLGEQFMVGEEICGAVVSVRFQEDIISIWNKTASDQAT 192

  Fly   189 VMEIGLKLRDLLVLPPHQ-LQYQLHKDTM 216
            ...|...||.:|.|||:. ::|:.|.|::
Mouse   193 TARIRDTLRRVLNLPPNTIMEYKTHTDSI 221

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF4E4	NP_648052.1	IF4E	53..209	CDD:460281	60/161 (37%)
Eif4e2	XP_036021474.1	IF4E	55..214	CDD:460281	60/161 (37%)