Protein Alignment eIF4E4 and ife-2

DIOPT Version :10

• Sequence 1: NP_648052.1
• Gene: eIF4E4 / 38743
• FlyBaseID: FBgn0035709
• Length: 229
• Species: Drosophila melanogaster
• Sequence 2: NP_508094.1
• Gene: ife-2 / 180393
• WormBaseID: WBGene00002060
• Length: 228
• Species: Caenorhabditis elegans
• Alignment Length: 210
• Identity: 77/210 - (36%)
• Similarity: 125/210 - (59%)
• Gaps: 19/210 - (9%)

  Fly    33 LSDMDIRKPVTEIVDLRLKHP---LENTWTLWYLENDRSKNWEDMQNEITSFDMVEDFWSLYNHI 94
            :|:..:..|.|      :.||   |:..||.|||.::|:|:||:....:.:|..|.:||:|::.|
 Worm     1 MSEEPVAAPGT------ISHPVYKLKRNWTWWYLNDERNKSWEERLKNVKTFSSVGEFWALHDSI 59

  Fly    95 KQPSEIRVGSDYSLFKKGIQPMWEDDANKFGGRWVINMGRGSKAE-LDKLWLDVLLILIGEAF-E 157
            |.||.:...|||::|:.||:||||...|:.||||:|.:.:|...| :|.:|.::|:.:|||.| :
 Worm    60 KPPSGLNPPSDYNVFRDGIEPMWEVPQNQNGGRWLITIEKGRTPEIMDTIWTEILMAMIGEQFSD 124

  Fly   158 NTEEVCGAVINLRGKSNKISIWTANGHNELAVMEIGLKLRDLL--VLPPHQ------LQYQLHKD 214
            :.|.:||.|.|:|||.:|||:||.|..::.|.:.||..|:.:|  ....||      |:|:.|:.
 Worm   125 DIESLCGIVCNVRGKGSKISVWTTNSADDGANLRIGGVLKQVLNNASMIHQRPLYDVLRYEDHES 189

  Fly   215 TMCKQGSVIKAVYCV 229
            ...|..|.:||.:.:
 Worm   190 CQKKTSSGVKAKHAI 204

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF4E4	NP_648052.1	IF4E	53..209	CDD:460281	67/168 (40%)
ife-2	NP_508094.1	IF4E	18..168	CDD:460281	62/149 (42%)