DRSC/TRiP Functional Genomics Resources

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Protein Alignment eIF4E4 and ife-5

DIOPT Version :9

Sequence 1:NP_648052.1 Gene:eIF4E4 / 38743 FlyBaseID:FBgn0035709 Length:229 Species:Drosophila melanogaster
Sequence 2:NP_001379255.1 Gene:ife-5 / 174871 WormBaseID:WBGene00002063 Length:201 Species:Caenorhabditis elegans


Alignment Length:184 Identity:68/184 - (36%)
Similarity:112/184 - (60%) Gaps:11/184 - (5%)


- Green bases have known domain annotations that are detailed below.


  Fly    52 HPLENTWTLWYLENDRSKNWEDMQNEITSFDMVEDFWSLYNHIKQPSEIRVGSDYSLFKKGIQPM 116
            :||:..|:.|:|.:||:.:|:|...::.:|:.|.:||:.|..|..||.:....||::|:..|||.
 Worm     9 YPLQRNWSWWFLNDDRNASWQDRLKKVYTFNTVPEFWAFYEAILPPSGLNDLCDYNVFRDDIQPK 73

  Fly   117 WEDDANKFGGRWVINMGRGSKAE-LDKLWLDVLLILIGEAF-ENTEEVCGAVINLRGKSNKISIW 179
            ||...|..||||:|.:.:|...| ||.:||::||.||||.| ::.|.:||.|.|:||:.:|||:|
 Worm    74 WEAPENWDGGRWLIIINKGKTPEVLDAVWLEILLALIGEQFGKDMESICGLVCNVRGQGSKISVW 138

  Fly   180 TANGHNELAVMEIGLKLRDLLVLPPHQ---------LQYQLHKDTMCKQGSVIK 224
            |.|.:::...|.||:.|::.|:....:         :.||.|::.:.|..|.:|
 Worm   139 TKNCNDDDTNMRIGVVLKEKLMAAASKAHSKPLFDVIHYQTHRNCVKKTTSALK 192

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
eIF4E4NP_648052.1 IF4E 56..209 CDD:279921 60/163 (37%)
ife-5NP_001379255.1 IF4E 10..159 CDD:396291 61/148 (41%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C160156161
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5053
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 1 0.950 - 0 Normalized mean entropy S964
OMA 1 1.010 - - QHG54586
OrthoDB 1 1.010 - - D1394271at2759
OrthoFinder 1 1.000 - - FOG0000666
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR11960
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X406
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
109.810

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