Protein Alignment GluRIA and GLR1.3

DIOPT Version :10

• Sequence 1: NP_476855.1
• Gene: GluRIA / 38742
• FlyBaseID: FBgn0004619
• Length: 991
• Species: Drosophila melanogaster
• Sequence 2: NP_199652.1
• Gene: GLR1.3 / 834896
• AraportID: AT5G48410
• Length: 860
• Species: Arabidopsis thaliana
• Alignment Length: 985
• Identity: 196/985 - (19%)
• Similarity: 353/985 - (35%)
• Gaps: 249/985 - (25%)

  Fly     5 LKFLAYLHFICASSIFWPEFSSAQQQQQTVSLTEKIPLGAIFEQGT-------DDVQSAFKYAML 62
            |.||..|....:.|     |:|.:..........:|.:|.:.:.|:       :.|..|..|...
plant    12 LSFLLVLLLFISRS-----FASTKNDDVDGGKRVQIRVGLVLDLGSLKGKIVKNSVSMALSYFYA 71

  Fly    63 NHN-----LNVSSRRFELQAYVDVINTADAFKLSRLICNQFSRGVYSMLGAVSPDSFDTLHSYSN 122
            .||     ::||.|....:..:.:.:..|..|         :.||.:::|..|......|.....
plant    72 IHNDYKTRVSVSLRNSHGEPLLALASAVDLLK---------TEGVEAIIGGNSLLEAKLLGELGE 127

  Fly   123 TFQMPFVTPWFPEKVLAPSSGLLD--FAISMRPDYH--QAIIDT----------IQYYGWQSIIY 173
            ..::|.::              ||  |::|:....|  ||..|:          |..:.|.|:..
plant   128 KARVPMIS--------------LDSPFSLSLSKYTHLIQATHDSTSEAKGITSFINVFDWNSVAL 178

  Fly   174 LYDSHDGLLRLQQIYQELKPGNETFRVQMVKRIANVTMAIEF----LHTLEDLGRFSKKRIVLDC 234
            :|:.||......|:..|....|.. |||. |....|:.:.:|    |..|:|||
plant   179 VYEDHDDWRESMQLLVEHFHENGV-RVQS-KVGFTVSSSEDFVMGRLQQLKDLG----------- 230

  Fly   235 PAEMAKEIIVQHVRDI------KLGRRTYHYLLSGLVMDNH-WPSDVVEFGAINITGFRIVDSNR 292
                 ..:.|.|:.::      ...||.      ||:.|.. |   ::....:|.....|.|..:
plant   231 -----TTVFVVHLSEVIATHLFPCARRL------GLMGDGFVW---ILTAKTMNSFHENIDDFTK 281

  Fly   293 RAVRDFHDSRKRLEPSGQSQSQNAGGPNSLPAISAQAALM-------YDAVFVLVEAFNRILRKK 350
            :|:......:..:..|.:.|:.......|||...|:...:       :|..|.|..|...|  :.
plant   282 QAMEGVVGFKSYIPMSIELQNFTLRWRKSLPVEEAELTRLSISGIWAHDIAFALARAAEVI--RM 344

  Fly   351 PDQFRSNHLQRRSHGGSSSSSATGTNESSALLDCNTSKGWVTPWEQGEKISRVLRKVEIDGLSGE 415
            |                        |.:|.||               |:|:    |...:||||:
plant   345 P------------------------NVTSTLL---------------EEIT----KTRFNGLSGD 366

  Fly   416 IRFDEDGRRINYTLHVVEMSVNSTLQQVAEWRDDAGLLPLHSHNYASSSRSASASTGDYDRNHTY 480
            .:.: |.:.::....::.| :.|:.::|       |.|   :.|.:.|:|...:||  :::..|.
plant   367 FQLN-DKKLLSNKFEIINM-IGSSERRV-------GFL---NSNGSFSNRRHLSST--HNKLETI 417

  Fly   481 IVSSLLEEPYLSLKQYTYGESLVGND------------RFEGYCKDLADMLAAQL---GIKYEIR 530
            |...       ...|...|.||:.:|            ||....|...|.:..:|   |...|:.
plant   418 IWPG-------GSAQSPKGTSLIDSDRKKLRVLVTSSNRFPRLMKVETDPVTNELIVEGFCIEVF 475

  Fly   531 LVQDGNYGAENQYAP----GGWDGMVGEL--IRKEADIAISAMTITAERERVIDFSKPFMTLGIS 589
            ......:..|.:|.|    ..:|.:...|  .:.:.|.|:..:|||:.|...:||:.||..:|:.
plant   476 RASISPFNYEVEYIPWLNGSNYDNLAYALHSQKDKYDAAVGDITITSNRSTYVDFTLPFTEMGLG 540

  Fly   590 IMIKKPVKQTPGVFSFLNPLSQEIWISVILSYVGVSFVLYFVTRFPPYEWRIVRRPQADSTAQQP 654
            |:   .||:. .::.|..||:.::||:....:|....:::.:.|....|::        .:..|.
plant   541 IV---AVKER-SMWVFFQPLTPDLWITSAFFFVLTGVIVWLIERAENKEFQ--------GSWPQQ 593

  Fly   655 PGIIGGATLSEPQAHVPPVPPNEFTMLNSFWYSLAAFMQQGCDITPPSIAGRIAAAVWWFFTIIL 719
            .|::                         .|:..:..:....:....::: |....||.|..:||
plant   594 IGVV-------------------------LWFGFSTLVYAHREKLKHNLS-RFVVTVWVFAVLIL 632

  Fly   720 ISSYTANLAAFLTVERMVAPIKTPEDLTMQTDVNYGTLLYGSTWEFFRRSQIGLHNKMWEYMNAN 784
            .:||||.|.:.:||::          :...::.:|...|.||.     .:.:.|.:.....|.:.
plant   633 TASYTATLTSMMTVQQ----------IRFNSNEDYVGHLSGSL-----IANVALTSSSLRAMRSL 682

  Fly   785 QHHSVHTYDEGIRRVRQSKGKYALLVESPKNEYVNARPPCDTMKVGRNIDTKGFGVATPIGSPLR 849
            ..:|...|.:.:    .:|....::.|.|..:.|....|.....|.....|.|||.....|..|.
plant   683 GLNSAADYAQAL----LNKTVSFVVDELPYLKVVLGENPTHFFMVKTQSTTNGFGFMFQKGFELV 743

  Fly   850 KRLNEAVLTLKENGELLRIRNKWWFDKTECNLDQETSTPNELSLSNVAGIYYILIGGLLLAVIVA 914
            ..::..:..|: ..|.|....|.|||........:||.|  ::|....|::.|:  |:..|..:|
plant   744 PNVSREISKLR-TSEKLNEMEKRWFDNQLPYTTDDTSNP--ITLYRFRGLFIII--GVSFAFALA 803

  Fly   915 IMEFFC-RNK 923
            ::...| |:|
plant   804 VLVILCLRDK 813

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIA	NP_476855.1	PBP1_iGluR_AMPA	41..456	CDD:380603	87/458 (19%)
		PBP2_iGluR_AMPA	477..879	CDD:270433	84/422 (20%)
		Lig_chan	610..906	CDD:459656	54/295 (18%)
GLR1.3	NP_199652.1	PBP1_GABAb_receptor_plant	43..405	CDD:380645	89/468 (19%)
		GluR_Plant	438..767	CDD:270404	74/386 (19%)