Protein Alignment GluRIA and ATGLR1.2

DIOPT Version :10

• Sequence 1: NP_476855.1
• Gene: GluRIA / 38742
• FlyBaseID: FBgn0004619
• Length: 991
• Species: Drosophila melanogaster
• Sequence 2: NP_199651.1
• Gene: ATGLR1.2 / 834895
• AraportID: AT5G48400
• Length: 867
• Species: Arabidopsis thaliana
• Alignment Length: 993
• Identity: 187/993 - (18%)
• Similarity: 359/993 - (36%)
• Gaps: 277/993 - (27%)

  Fly     5 LKFLAYLHFICASSIFWPEFSSAQQQQQTVSLTEKIPLGAIFEQGTDD---VQSAFKYAML---- 62
            |.||..|.|..::.     |:|:|.......:  ::.:|.:.:.|:.:   |:|:...|:.
plant    12 LSFLLVLLFFISNC-----FASSQNNDDDKRI--RVRVGLVLDLGSVEGKIVRSSVSMALSDFYD 69

  Fly    63 NHN-------LNVSSRRFE----LQAYVDVINTADAFKLSRLICNQFSRGVYSMLGAVSPDSFDT 116
            |||       |.|.....|    |.:.||::.|               .||.:::|..|......
plant    70 NHNDYKTRLSLLVRDSHGEPLLALDSVVDLLQT---------------EGVQAIIGGNSLLEAKL 119

  Fly   117 LHSYSNTFQMPFVTPWFPEKVLAPSS-GLLDFAISMRPDYHQA-----IIDTIQYYGWQSIIYLY 175
            |.......::|.::      :.:|.| .|..:...::..::.|     |...:..:.|.|:..:.
plant   120 LAELGEKARVPVIS------LNSPMSLSLSKYTHLIQATHNSASEVKGITAFLHGFDWNSVALVL 178

  Fly   176 DSHDGLLRLQQIYQELKPGNETFRVQMVKRIANVTMAIEFLHTLEDLGRFSKKRIVLDCPAEM-- 238
            :.||                 .:|              |.:|.:.|  .|.:..:.:......
plant   179 EDHD-----------------DWR--------------ESMHFMVD--HFHENNVHVQSKVAFSV 210

  Fly   239 --AKEIIVQHVRDIK-LGRRTYHYLLSGLVMDNHWPSDVVEFGAINITGFRIVDSNRRAVRDFHD 300
              :::.::..:|::| ||...:...||.::....:|. ..:.|.:. .||..:.:: |::..|||
plant   211 TSSEDSLMDRLRELKDLGTTVFVVHLSEVIATRLFPC-AEKLGMMG-EGFAWILTS-RSMSSFHD 272

  Fly   301 SRKRLEPSGQSQSQNAGGPNSLPAISAQAALMYDAVFVLVEAFNRILRKKP----DQFRSNHLQR 361
              :.::...:...:...|..|...:|.             |..|..||.:.    ::...:.:.|
plant   273 --QFIDDLTKEAMEGVVGFKSYIPMSK-------------ELHNFTLRWRKTLPVEEVTGSEITR 322

  Fly   362 RSHGG--------SSSSSATGT---NESSALLDCNTSKGWVTPWEQGEKISRVLRKVEIDGLSGE 415
            .|..|        |.:|:|..|   ..:|.||:                   .:::....||||.
plant   323 LSISGVWAHDVAWSLASAAEVTRMPTVTSTLLE-------------------AIKESRFKGLSGN 368

  Fly   416 IRFDEDGRRINYTLHVVEMSVNSTLQQVAEWRDDAGLLPLHSHNYASSSRSASASTGDYDRNHTY 480
            .:.| |.:.::....:|.| :.|..::|..|          :.|.:.|:|...:||  :|...|.
plant   369 FQLD-DMKLLSDKFEIVNM-IGSGERRVGFW----------NSNGSFSNRRQLSST--HDNLETI 419

  Fly   481 I----------VSSLLEEPYLSLKQYTYGESLVGNDRF------------------EGYCKDLAD 517
            |          ..||.|.....|:..     :..::||                  ||:|.::..
plant   420 IWPGGSAQSPKGRSLRESGRKKLRVL-----VTSSNRFPRLMKVETDPITHEITIVEGFCIEVFQ 479

  Fly   518 MLAAQLGIKYE-IRLVQDGNYGAENQYAPGGWDGMVGELIRKEADIAISAMTITAERERVIDFSK 581
            ...|....:.| ||.:...|| .:..||....        :.:.|.|:..:|||::|...:||:.
plant   480 ASIAPFNYEVEYIRWLNGTNY-TKLAYALHSQ--------KDKYDAAVGDITITSDRSMYVDFTL 535

  Fly   582 PFMTLGISIMIKKPVKQTPGVFSFLNPLSQEIWISVILSYVGVSFVLYFVTRFPPYEWRIVRRPQ 646
            |:..:|:.|:..|    ...::.|..||:..:||:....:|....:::.:.|....|::
plant   536 PYTEMGLGIVAAK----ERSMWVFFQPLTPNLWITSAAFFVLTGIIVWLIERAENKEFQ------ 590

  Fly   647 ADSTAQQPPGIIGGATLSEPQAHVPPVPPNEFTMLNSFWYSLAAFMQQGCDITPPSIAGRIAAAV 711
              .:..|..|::                         .|:..:..:....:....::: |....|
plant   591 --GSWPQQIGVV-------------------------IWFGFSTLVYAHREKLQHNLS-RFVVTV 627

  Fly   712 WWFFTIILISSYTANLAAFLTVERMVAPIKTPEDLTMQTDVNYGTLLYGS-------TWEFFRRS 769
            |.|..:||::||||.|.:.:||::          :....:.:|...|.||       |....|..
plant   628 WVFAVLILVTSYTATLTSMMTVQQ----------IRFNANEDYVGHLSGSLIANAALTNSSLRAM 682

  Fly   770 Q-IGLHNKMWEYMNANQHHSVHTYDEGIRRVRQSKGKYALLVESPKNEYVNARPPCDTMKVGRNI 833
            : :|| |...:|..|..:.|| :|               ::.|.|..:.:....|...:.|....
plant   683 RLLGL-NTSEDYAQALMNKSV-SY---------------IVSELPYLKILLGENPGHFLMVKTQS 730

  Fly   834 DTKGFGVATPIGSPLRKRLNEAVLTLKENGELLRIRNKWWFDKTECNLDQETSTPNELSLSNVAG 898
            .|.|||.....||.|...::..:..|: ..|.|....:.||||.......:||.|  ::|....|
plant   731 TTNGFGFMFQKGSELAPNVSREIAKLR-TSERLNEMERRWFDKQLPYTTDDTSNP--ITLYRFRG 792

  Fly   899 IYYILIGGLLLAVIVAIM 916
            ::  :|.|:..|..:|::
plant   793 LF--MITGVSFAFALAVL 808

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIA	NP_476855.1	PBP1_iGluR_AMPA	41..456	CDD:380603	77/458 (17%)
		PBP2_iGluR_AMPA	477..879	CDD:270433	87/438 (20%)
		Lig_chan	610..906	CDD:459656	59/303 (19%)
ATGLR1.2	NP_199651.1	PBP1_GABAb_receptor_plant	41..407	CDD:380645	79/468 (17%)
		GluR_Plant	440..770	CDD:270404	78/409 (19%)