Protein Alignment GluRIA and GLR5

DIOPT Version :10

• Sequence 1: NP_476855.1
• Gene: GluRIA / 38742
• FlyBaseID: FBgn0004619
• Length: 991
• Species: Drosophila melanogaster
• Sequence 2: NP_565744.1
• Gene: GLR5 / 817801
• AraportID: AT2G32400
• Length: 921
• Species: Arabidopsis thaliana
• Alignment Length: 1002
• Identity: 220/1002 - (21%)
• Similarity: 386/1002 - (38%)
• Gaps: 253/1002 - (25%)

  Fly    29 QQQQTVSLTEKIPLGAIFEQGTDDVQSAFKYAMLNHNLNVSSR--RFELQAYVDVINTADAF--- 88
            |:.|.|:      :||:|         ||.        :|..|  :..|:|.|..:|...:|
plant    26 QRPQLVN------IGAVF---------AFD--------SVIGRAAKVALEAAVSDVNNDKSFLKE 67

  Fly    89 -KLSRLI----CNQFSRG-----------VYSMLGAVSPDSFDTLHSYSNTFQMPFVTPWFPEKV 137
             :|..|:    ||.| ||           |.:|:|.:|.....|:...:.....|.|:    ...
plant    68 TELRLLMEDSACNVF-RGSFGAFELLEKEVVAMIGPISSSVAHTISDIAKGLHFPLVS----FAA 127

  Fly   138 LAPSSGLLDFAISMRP---DYHQ--AIIDTIQYYGWQSIIYLYDSHDGLLRLQQIYQELKPGNET 197
            ..|:...|.|...:|.   |.||  |::|.|.:|||:.:|.:| |.|.|.|         .|...
plant   128 TDPTLSALQFPFFLRTTPNDAHQMSALVDLINFYGWKEVISVY-SDDELGR---------NGVSA 182

  Fly   198 FRVQMVKRIANVTMAIEF-LHTLEDLGRFSKKRIVLDCPAEMAKEIIVQH--------VRDI--K 251
            ...::.|:.:.::..:.. :|:.|   :|...  .|:....:...:.:.|        :.||  |
plant   183 LDDELYKKRSRISYKVPLSVHSDE---KFLTN--ALNKSKSIGPRVYILHFGPDPLLRIFDIAQK 242

  Fly   252 LGRRTYHYLLSGLVMDNHWPSDVVEFGAINITGFRIVDSNRRAVRDFHDSRKRLE---------P 307
            |...|:.|:  .|..|  |         :::|...:.|..         :.||||         |
plant   243 LQMMTHEYV--WLATD--W---------LSVTLDSLSDKG---------TLKRLEGVVGLRQHIP 285

  Fly   308 SGQSQSQNAGGPNSLPAISAQAALMYDAVFVLVEAFNRILRKKPDQFRSNHLQRRSHGGSSSSSA 372
            .............|..:::|.|...||.|:::......:|.:
plant   286 ESVKMEHFTHKLQSNRSMNAYALHAYDTVWMIAHGIEELLNE----------------------- 327

  Fly   373 TGTN----ESSALLDCNTSK---GWVTPWEQGEKISRVLRKVEIDGLSGEIRFDEDGRRI---NY 427
             |.|    .|..||....:|   ..:..:..||.:...|.||...|::|:::|. .||.:   :|
plant   328 -GINITFSYSEKLLHARGTKLHLEKIKFFNSGELLLEKLLKVNFTGIAGQVQFG-SGRNVIGCDY 390

  Fly   428 TLHVVEMSVNST-LQQVAEWRDDAG---LLPLHSHNYASSSRSASASTGDY-------DRNHTYI 481
            .:    ::||.| :..|..|..:.|   :.|...|:...:|..:....||.       ::...::
plant   391 EI----INVNKTDVHTVGFWSKNGGFSVVAPKTRHSQKKTSFVSDEKLGDITWPGGGREKPRGWV 451

  Fly   482 VS------SLLEEPYLSLKQYTYGESLVGNDRFEGYCKDLADMLAAQLGIKYEIRLVQD--GNYG 538
            ::      .::....:|..::. .|....:.|.:|:|.|:  .:.|...:.|.:..:.:  ||..
plant   452 IADSADPLKIVVPRRVSFVEFV-TEEKNSSHRIQGFCIDV--FIEALKFVPYSVPYIFEPFGNGH 513

  Fly   539 AENQY-------APGGWDGMVGELIRKEADIAISAMTITAERERVIDFSKPFMTLGISIMIKKPV 596
            :...|       ..|.:|..||       |||     |...|.:::|||:|:.:.|:.::|  |.
plant   514 SSPNYNHLIQMVTDGVYDAAVG-------DIA-----IVPSRSKLVDFSQPYASTGLVVVI--PA 564

  Fly   597 KQTPGVFSFLNPLSQEIWISVILSYVGVSFVLYFVTRFPPYEWRIVRRPQADSTAQQPPGIIGGA 661
            ......:.||.|.:..:|..|::|::.::.|:          |.:..|...|...
plant   565 NDDNATWIFLRPFTSRLWCVVLVSFLVIAVVI----------WILEHRINEDFRG---------- 609

  Fly   662 TLSEPQAHVPPVPPNE--FTMLNSFWYSLAAFMQQGCDITPPSIAGRIAAAVWWFFTIILISSYT 724
                        ||..  .|||   .:|.:...::..:.|..::| |:...||.|..::|.:|||
plant   610 ------------PPRRQLSTML---LFSFSTLFKRNQEDTISNLA-RLVMIVWLFLLMVLTASYT 658

  Fly   725 ANLAAFLTVERMVAPIKTPEDLTMQTDVNYGTLLYGSTWEFFRRSQIGLHNKMWEYMNANQHHSV 789
            |||.:.|||:::.:.| |..|....::|..|......|.|:...| :|:.......::     |.
plant   659 ANLTSILTVQQLPSAI-TGIDSLRASEVPIGYQAGTFTLEYLTYS-LGMARSRLVPLD-----ST 716

  Fly   790 HTYDEGIRRVRQSKGKYALLV-ESPKNEYVNARPPCDTMKVGRNIDTKGFGVATPIGSPLRKRLN 853
            ..|::.::....:.|..|.:| |.|..|...|......: ||.....:|:|.|....|||...::
plant   717 EEYEKALKLGPTNWGGVAAIVDELPYIELFLAERTGFKI-VGEPFMHRGWGFAFKRDSPLAIDMS 780

  Fly   854 EAVLTLKENGELLRIRNKWWFDKTEC----NLDQETSTPNELSLSNVAGIYYILIGGLLLAVIVA 914
            .|:|.|.|..:|..||.| |..||.|    |.:.|   ||:|.|.:..|:|.:.|...:.|.:|.
plant   781 TAILKLSETRKLQEIRKK-WLCKTNCAGKSNWNPE---PNQLHLKSFKGLYLVCIAITVSAFLVF 841

  Fly   915 IMEF---FCRNKTPQLKS--PGSNGSA 936
            ::..   |.|.:..:..|  |.::.||
plant   842 VLRMIRQFVRYRRMERTSSMPRASWSA 868

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIA	NP_476855.1	PBP1_iGluR_AMPA	41..456	CDD:380603	99/474 (21%)
		PBP2_iGluR_AMPA	477..879	CDD:270433	96/419 (23%)
		Lig_chan	610..906	CDD:459656	76/302 (25%)
GLR5	NP_565744.1	PBP1_GABAb_receptor_plant	32..416	CDD:380645	98/477 (21%)
		GluR_Plant	458..800	CDD:270404	93/403 (23%)
		Lig_chan	578..832	CDD:459656	75/301 (25%)