Protein Alignment GluRIA and GLR3.5

DIOPT Version :10

• Sequence 1: NP_476855.1
• Gene: GluRIA / 38742
• FlyBaseID: FBgn0004619
• Length: 991
• Species: Drosophila melanogaster
• Sequence 2: NP_001324013.1
• Gene: GLR3.5 / 817800
• AraportID: AT2G32390
• Length: 953
• Species: Arabidopsis thaliana
• Alignment Length: 993
• Identity: 219/993 - (22%)
• Similarity: 374/993 - (37%)
• Gaps: 225/993 - (22%)

  Fly    14 ICASSIFWPEFSSA-----QQQQQTVSLTEKIPLGAIFEQGTDD------VQSAFKYAMLNHNLN 67
            :|.|:::......|     .:...:.||...:.:||:|   |.|      .:.||..|:.:.|.:
plant    17 LCISALWVLPIQGAGRESFSRNSSSSSLPSSVNVGALF---TYDSFIGRAAKLAFVAAIEDINAD 78

  Fly    68 VSSRR-------FELQAYVDVINTADAFKLSRLICNQFSRGVYSMLGAVSPDSFDTLHSYS---N 122
            .|..|       |:.......:.|..|.:|..          ..::.|:.|.|....|..|   |
plant    79 QSILRGTKLNIVFQDTNCSGFVGTMGALQLME----------NKVVAAIGPQSSGIGHIISHVAN 133

  Fly   123 TFQMPFVTPWFPEKVLAPSSGLLDFAISMRP---DYHQ--AIIDTIQYYGWQSIIYLY-DSHDGL 181
            ...:||::    .....|:...|.:...:|.   ||.|  ||.|.:.|:.|:.::.:: |...|
plant   134 ELHVPFLS----FAATDPTLSSLQYPYFLRTTQNDYFQMNAITDFVSYFRWREVVAIFVDDEYG- 193

  Fly   182 LRLQQIYQELKPGNETFRVQMVKRIANVTMAIEF-----LHTLEDLGRFSKKRIVLDCPAEMAKE 241
                      :.|.......:.|:.|.::....|     ..::.||         |.....|...
plant   194 ----------RNGISVLGDALAKKRAKISYKAAFPPGADNSSISDL---------LASVNLMESR 239

  Fly   242 IIVQHVRD----------IKLGRR-------TYHYLLSGLVMDNHWPSDVVEFGAI-NITGFRIV 288
            |.|.||..          ..||..       |..:||:.|  |:..|.|......: .:..||..
plant   240 IFVVHVNPDSGLNIFSVAKSLGMMGSGYVWITTDWLLTAL--DSMEPLDPRALDLLQGVVAFRHY 302

  Fly   289 DSNRRAVRDFHDSRKRLEPSGQSQSQNAGGPNSLPAISAQAALMYDAVFVLVEAFNRILRKKPDQ 353
            .......|.|....|.|......:|.:  |.||      .|...||:|:::..|.        |.
plant   303 TPESDNKRQFKGRWKNLRFKESLKSDD--GFNS------YALYAYDSVWLVARAL--------DV 351

  Fly   354 FRSNHLQRRSHGGSSSSSATGTNESSALLDCNTSKGWVTPWEQGEKISRVLRKVEIDGLSGEIRF 418
            |.|   |..:...|:..|...||:|...|    ||..:  :.:||:..:|:.::...||:|:|.|
plant   352 FFS---QGNTVTFSNDPSLRNTNDSGIKL----SKLHI--FNEGERFLQVILEMNYTGLTGQIEF 407

  Fly   419 DEDGRRINYTLHVVEMSVNSTLQQVAEWRDDAGLLPLHSHNYASSSRSASASTGDYDRNHTYIVS 483
            :.:..|||....::.:.....| :|..|.:..|..........|...:.||.  |...|......
plant   408 NSEKNRINPAYDILNIKSTGPL-RVGYWSNHTGFSVAPPETLYSKPSNTSAK--DQRLNEIIWPG 469

  Fly   484 SLLEEP------------------YLSLKQYTYGESLVGNDR----FEGYCKDLADMLAAQLGIK 526
            .:::.|                  .:|.|.|      ...|:    .:|:|.|:.: .|.|| :.
plant   470 EVIKPPRGWVFPENGKPLKIGVPNRVSYKNY------ASKDKNPLGVKGFCIDIFE-AAIQL-LP 526

  Fly   527 YEIR----LVQDGNYGAENQYAPGGWDGMVGELIRKEADIAISAMTITAERERVIDFSKPFMTLG 587
            |.:.    |..||....       .:|.::.|:.....|:|:..:||...|.:.:||::||:..|
plant   527 YPVPRTYILYGDGKKNP-------SYDNLISEVAANIFDVAVGDVTIITNRTKFVDFTQPFIESG 584

  Fly   588 ISIMIK-KPVKQTPGVFSFLNPLSQEIWISVILSYVGVSFVLYFVTRFPPYEWRIVRRPQADSTA 651
            :.::.. |..|.:|  :|||.|.:.|:|......::.|..|::.:......|:|
plant   585 LVVVAPVKGAKSSP--WSFLKPFTIEMWAVTGALFLFVGAVIWILEHRFNEEFR----------- 636

  Fly   652 QQPPGIIGGATLSEPQAHVPPVPPNEFTMLNSFWYSLAAFMQQGCDITPPSIAGRIAAAVWWFFT 716
                                 .||.. .::..||:|.:.......:.| .|..||....||.|..
plant   637 ---------------------GPPRR-QIITVFWFSFSTMFFSHRENT-VSTLGRFVLLVWLFVV 678

  Fly   717 IILISSYTANLAAFLTVERMVAPIKTPEDLTMQTD---VNYGTLLYGSTWEFFRRSQIGLHNKMW 778
            :|:.|||||:|.:.|||:::.:.|:..:.|....:   |..||.    .|:|       |.|:
plant   679 LIINSSYTASLTSILTVQQLTSRIEGMDTLIASNEPIGVQDGTF----AWKF-------LVNE-- 730

  Fly   779 EYMNANQHHSVHTYDE-----GIRRVRQSKGKYALLVESPKNEYVNARPPCDTMKVGRNIDTKGF 838
              :|......:...||     .::|..:..|..|::.|.|..:.:.:...|....||:.....|:
plant   731 --LNIAPSRIIPLKDEEEYLSALQRGPRGGGVAAIVDELPYIKALLSNSNCKFRTVGQEFTRTGW 793

  Fly   839 GVATPIGSPLRKRLNEAVLTLKENGELLRIRNKWWFDKTECNLDQETSTPN-ELSLSNVAGIYYI 902
            |.|....|||...::.|:|.|.|.|:|.:||.||.....||.: |.:.|.| ::|:.:..|::
plant   794 GFAFQRDSPLAVDMSTAILQLAEEGKLEKIRKKWLTYDHECTM-QISDTENYQISVQSFWGLF-- 855

  Fly   903 LIGGLLLAVIVAIMEFFC 920
            ||.|::..:.:.:   ||
plant   856 LICGVVWFIALTL---FC 870

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIA	NP_476855.1	PBP1_iGluR_AMPA	41..456	CDD:380603	99/459 (22%)
		PBP2_iGluR_AMPA	477..879	CDD:270433	99/436 (23%)
		Lig_chan	610..906	CDD:459656	73/304 (24%)
GLR3.5	NP_001324013.1	PBP1_GABAb_receptor_plant	49..444	CDD:380645	99/459 (22%)
		GluR_Plant	485..828	CDD:270404	96/408 (24%)