Protein Alignment GluRIA and LOC4576285

DIOPT Version :10

• Sequence 1: NP_476855.1
• Gene: GluRIA / 38742
• FlyBaseID: FBgn0004619
• Length: 991
• Species: Drosophila melanogaster
• Sequence 2: XP_061502502.1
• Gene: LOC4576285 / 4576285
• VectorBaseID: AGAMI1_009844
• Length: 456
• Species: Anopheles gambiae
• Alignment Length: 579
• Identity: 304/579 - (52%)
• Similarity: 373/579 - (64%)
• Gaps: 123/579 - (21%)

  Fly   105 MLGAVSPDSFDTLHSYSNTFQMPFVTPWFPEKVLAPSSGLLDFAISMRPDYHQAIIDTIQYYGWQ 169
            ||||||||||||||.|||||||||||||||||||.||||.||||||||||::||||||::||||.
Mosquito     1 MLGAVSPDSFDTLHPYSNTFQMPFVTPWFPEKVLTPSSGFLDFAISMRPDHYQAIIDTVRYYGWD 65

  Fly   170 SIIYLYDSHDGLLRLQQIYQELKPGNETFRVQMVKRIANVTMAIEFLHTLEDLGRFSKKRIVLDC 234
            .|||:|||||||||||||||.|:||||||.|:.|||||||:.|||||.|:|:|.|:|:|.|||||
Mosquito    66 RIIYMYDSHDGLLRLQQIYQGLRPGNETFHVETVKRIANVSDAIEFLRTIEELNRWSRKHIVLDC 130

  Fly   235 PAEMAKEIIVQHVRDIKLGRRTYHYLLSGLVMDNHWPSDVVEFGAINITGFRIVDSNRRAVRDFH 299
            ..|:||:|:|.|||||.||:|||||||||||||:.|.|:|:|:||||||||||||::::.|::|.
Mosquito   131 STELAKDIVVSHVRDITLGKRTYHYLLSGLVMDDRWESEVIEYGAINITGFRIVDTSKKYVKEFL 195

  Fly   300 DSRKRLEPSGQSQSQNAGGPNSLPAISAQAALMYDAVFVLVEAFNRILRKKPDQFRSNHLQRRSH 364
            |..|||:|   :.||.||    ...|||||||||||||||||||::|:||||||||:..:  |:.
Mosquito   196 DGWKRLDP---TTSQGAG----KELISAQAALMYDAVFVLVEAFSKIMRKKPDQFRAYTM--RNR 251

  Fly   365 GGSSSSSATGTNESSALLDCNTSKGWVTPWEQGEKISRVLRKVEIDGLSGEIRFDEDGRRINYTL 429
            |...:..|.||.    .||||||||||||||.|:||||.||||||.||:|:|||:|||:|.||||
Mosquito   252 GQPFNLPANGTR----TLDCNTSKGWVTPWEHGDKISRYLRKVEISGLTGDIRFNEDGKRQNYTL 312

  Fly   430 HVVEMSVNSTLQQVAEWRDDAGLLPLHSHNYASSSRSASASTGDYDRNHTYIVSSLLEEPYLSLK 494
            |||||:|||.:.:||||.|:.||.|:    .|..:|..:..  .|:||.||||::::||||:.|:
Mosquito   313 HVVEMTVNSAMVKVAEWSDEGGLAPV----VAKYTRLKTDM--HYERNKTYIVTTIIEEPYIMLR 371

  Fly   495 QYTYGESLVGNDRFEGYCKDLADMLAAQLGIKYEIRLVQDGNYGAENQYAPGGWDGMVGELIRKE 559
            |...||:|..|:||||||||||:::|.:|||          |....:|
Mosquito   372 QPEPGETLETNERFEGYCKDLAELVAKKLGI----------NCPRASQ----------------- 409

  Fly   560 ADIAISAMTITAERERVIDFSKPFMTLGISIMIKKPVKQTPGVFSFLNPLSQEIWISVILSYVGV 624
                       ..|.:.||
Mosquito   410 -----------LRRCQSID---------------------------------------------- 417

  Fly   625 SFVLYFVTRFPPYEWRIVRRPQADSTAQQPPGIIGGATLSEPQAHVPPVPPNEFTMLNS 683
              |||.|:||.|:|||:|     :...:||..             ||....|||:.|:|
Mosquito   418 --VLYIVSRFSPFEWRLV-----NYNDEQPDA-------------VPQATANEFSALSS 456

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIA	NP_476855.1	PBP1_iGluR_AMPA	41..456	CDD:380603	246/350 (70%)
		PBP2_iGluR_AMPA	477..879	CDD:270433	54/207 (26%)
		Lig_chan	610..906	CDD:459656	20/74 (27%)
LOC4576285	XP_061502502.1	None