Protein Alignment GluRIA and Ir84a

DIOPT Version :9

• Sequence 1: NP_476855.1
• Gene: GluRIA / 38742
• FlyBaseID: FBgn0004619
• Length: 991
• Species: Drosophila melanogaster
• Sequence 2: NP_649720.2
• Gene: Ir84a / 40891
• FlyBaseID: FBgn0037501
• Length: 644
• Species: Drosophila melanogaster
• Alignment Length: 597
• Identity: 116/597 - (19%)
• Similarity: 215/597 - (36%)
• Gaps: 155/597 - (25%)

  Fly   385 NTSKGWV--------TPWEQGEKISRVLR--KVEIDG-LSGEIRFDEDGRRINYTLHVVEMSVNS 438
            |.|..|.        .|.||  .|.::|.  ::.||. ::..:|..::...:.|.::.:....|:
  Fly   125 NNSLAWFILGSGRESLPVEQ--LIDQLLSGYRMGIDADITVALRGPDNASMLFYDVYRISRQANT 187

  Fly   439 TL--QQVAEWRDDAGLLPLHSHNYASSSRSASASTGDYD-----RNHTYIVSSLLEEPYLSLKQY 496
            .|  ::...|        .||..|        ...|::.     |...::..:|:....|:.|..
  Fly   188 PLIIEKKGLW--------THSGGY--------QKFGNFKNTWVIRRRNFLNVTLIGSTVLTEKPP 236

  Fly   497 TYGE--------SLVGNDRFEGYCKDLADMLAAQLGIKYEIRLVQDGNYGAENQYAPGGWDGMVG 553
            .:|:        .|...|..:.....|..::.....:...|.|........:|    |.|.|::|
  Fly   237 GFGDMEYLADDKQLQQLDPMQRKTYQLFQLVERMFNLSLAISLTDKWGELLDN----GSWSGVMG 297

  Fly   554 ELIRKEADIAISAMTITAERERVIDFSKPFMTLGISIMIKKP----VKQTPGVFSFLNPLSQEIW 614
            ::..:|||.|:..:....:|:..:.:|....|..|..:.:.|    :|..     |..|||.::|
  Fly   298 QVTSREADFAVCPIRFVLDRQPYVQYSAVLHTQNIHFLFRHPRRSHIKNI-----FFEPLSNQVW 357

  Fly   615 ISVILSYVGVSFVLYFVTRFPPYEWRIVRRPQADSTAQQPPGIIGGATLSEPQAHVPPVPPNEFT 679
            ..|:....|.:.:|.|..|..                         ..||..:        |.|:
  Fly   358 WCVLALVTGSTILLLFHVRLE-------------------------RMLSNME--------NRFS 389

  Fly   680 MLNSFWYS-LAAFMQQGCDITPPS-----IAGRIAAAVWWFFTIILISSYTANLAAFLTVERMVA 738
            .:   |:: |..::|||    |.:     .:.|:..::...|:.:|:..|.|.:...|..|
  Fly   390 FV---WFTMLETYLQQG----PANEIFRLFSTRLLISLSCIFSFMLMQFYGAFIVGSLLSE---- 443

  Fly   739 PIKTPEDLTMQTDVNYGTLLYGSTWEFFRRSQIGLHNKMWEY----MNANQ-------------- 785
                    :.::.||. ..||.|      ...||:.|..:.:    ..:||
  Fly   444 --------SARSIVNL-QALYDS------NLAIGMENISYNFPIFTNTSNQLVRDVYVKKICKSG 493

  Fly   786 HHSVHTYDEGIRRVRQSK--------GKYALLVESPKNEYVNARPPCDTMKVGRNIDTKGFGVAT 842
            .|::.:..:|..|:.|.:        ..|.||:|...:|    ...||..:|..|:.... |...
  Fly   494 EHNIMSLQQGAERIIQGRFAFHTAIDRMYRLLLELQMDE----AEFCDLQEVMFNLPYDS-GSVM 553

  Fly   843 PIGSPLRKRLNEAVLTLKENGELLRIRNKWWFDKTECNLDQETSTPNELSLSNVAGIYYILIGGL 907
            |.|||.|:.|..|:|..:..|.|.....||...:.:|:|.:.:..  |:.|.:.|...:.|...:
  Fly   554 PKGSPWREHLAHALLHFRATGLLQYNDKKWMVRRPDCSLFKTSQA--EVDLEHFAPALFALALAM 616

  Fly   908 LLAVIVAIMEFF 919
            :.:.:|.::|.|
  Fly   617 VASALVFLLELF 628

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIA	NP_476855.1	PBP1_iGluR_AMPA	41..453	CDD:107375	15/80 (19%)
		ANF_receptor	53..434	CDD:279440	12/59 (20%)
		PBP2_iGluR_AMPA	477..879	CDD:270433	87/445 (20%)
		Lig_chan	612..907	CDD:278489	65/326 (20%)
Ir84a	NP_649720.2	nt_trans	<54..>112	CDD:294020
		Periplasmic_Binding_Protein_Type_2	222..583	CDD:304360	85/433 (20%)
		Lig_chan	355..602	CDD:278489	62/312 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462539
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940