Protein Alignment GluRIA and Ir75c

DIOPT Version :9

• Sequence 1: NP_476855.1
• Gene: GluRIA / 38742
• FlyBaseID: FBgn0004619
• Length: 991
• Species: Drosophila melanogaster
• Sequence 2: NP_649013.3
• Gene: Ir75c / 39983
• FlyBaseID: FBgn0261401
• Length: 623
• Species: Drosophila melanogaster
• Alignment Length: 667
• Identity: 125/667 - (18%)
• Similarity: 244/667 - (36%)
• Gaps: 182/667 - (27%)

  Fly   337 FVLVEAFNR-------ILRKKPDQFRSNHLQRRSHG----------GSSSSSATGTNESSALLDC 384
            |.|||..|:       |..:.||...:.|.:.....          |...:... ||:||.....
  Fly    34 FPLVEMLNQNGIFSQYIDVQNPDNLANVHKEYLDSDLVRLGVFLDLGCDKAELV-TNQSSRARLY 97

  Fly   385 NTSKGWVTPWEQGE--KISRVLRKVEIDGLSGEIRF--DEDGRRINYTLHVV-----------EM 434
            |.:..|:...|.|.  |::::.....: .|:.::.:  .||..|  :.||.|           .:
  Fly    98 NQNLHWLLYDEAGNFTKLTQLFEGANL-SLNADVTYVSREDEER--FILHDVYNKGSHLGGKLNI 159

  Fly   435 SVNSTLQ------QVAEWRDDAGLLPLHSHNYASSS---RSASASTGDYDRNHTYIVS------- 483
            :|:.|||      ||.|:..:..|.|...|....||   |.|:            :||
  Fly   160 TVDQTLQCNRSHCQVKEYLSELHLRPRLQHRMDLSSVTFRLAA------------LVSVLPINSS 212

  Fly   484 --SLLEEPYLSLKQYTYGESL--VGNDRFEGYCKDLADMLAAQLGIKYEIRLVQDGNYGAENQYA 544
              .|||  :|:..:.::.:|:  :|| |...:.:::       ||.|  :..:..|.:..::.:.
  Fly   213 EEELLE--FLNSDRDSHMDSISRIGN-RLIMHTQEI-------LGFK--LHYIWCGTWSVQDAFG 265

  Fly   545 PGGWDGMVGELIRKEADIA-------------ISAMTITAERERVIDFSKPFMTLGISIMIKKPV 596
                 |.:|.|..:.|::.             :..||..|:...|..|..|. ..||...:
  Fly   266 -----GAIGMLTNESAELCTTPFVPSWNRLHYLHPMTEQAQFRAVCMFRTPH-NAGIKAAV---- 320

  Fly   597 KQTPGVFSFLNPLSQEIWISV--ILSYVGV-SFVLYFVTRFPPYEWRIVRRPQADSTAQQPPGII 658
                    ||.|....:|.:.  :|.:.|| .::::.:.|    .|.
  Fly   321 --------FLEPFMPSVWFAFAGLLIFAGVLLWMIFHLER----HWM------------------ 355

  Fly   659 GGATLSEPQAHVPPVPPNEFTMLNSFWYSLAAFMQQGCDITPPSIAGRIAAAVWWFFTIILISSY 723
                    |..:..:|    ::|:|...|..|...||..:.|.|..||:|.......:.::.:.|
  Fly   356 --------QRCLDFIP----SLLSSCLISFGAACIQGSYLMPKSAGGRLAFIAVMLTSFLMYNYY 408

  Fly   724 TANLAAFLTVERMVAPIKTPEDLT-MQTDVNYGTLLYGSTW----------EFFRRSQIGLH--N 775
            |:.:.:.|....:.:.|:|.:.|. ...||.:.|:.:..|:          ..:::......  |
  Fly   409 TSIVVSTLLGSPVRSNIRTIQQLADSSLDVGFDTVPFTKTYLVSSPRPDIRSLYKQKVESKRDPN 473

  Fly   776 KMWEYMNANQHHSVHTYDEGIRRVRQSKG-----KYALLVESPKNEYVNARPPCDTMKVGRNIDT 835
            .:|           .:.:||:.|||...|     :.:.:....:..|: .|...|..::....::
  Fly   474 SVW-----------LSPEEGVIRVRDQPGFVYTSEASFMYHFVEKHYL-PREISDLNEIILRPES 526

  Fly   836 KGFGVATPIGSPLRKRLNEAVLTLKENGELLRIRNKWWFDKTECNLDQETSTPNELSLSNVAGIY 900
            ..:|: ..:.|..|:.|.:..:.:.|.|  :..:...:|.||:.: ....|...::.:...|.::
  Fly   527 AVYGM-VHLNSTYRQLLTQLQVRMLETG--ITSKQSRFFSKTKLH-TFSNSFVIQVGMEYAAPLF 587

  Fly   901 YILIGGLLLAVIVAIME 917
            ..|:....||:::.|:|
  Fly   588 ISLLVAYFLALLILILE 604

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIA	NP_476855.1	PBP1_iGluR_AMPA	41..453	CDD:107375	33/153 (22%)
		ANF_receptor	53..434	CDD:279440	26/128 (20%)
		PBP2_iGluR_AMPA	477..879	CDD:270433	78/446 (17%)
		Lig_chan	612..907	CDD:278489	52/315 (17%)
Ir75c	NP_649013.3	Lig_chan	328..553	CDD:306551	45/271 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462522
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840