Protein Alignment GluRIA and Ir75a

DIOPT Version :9

• Sequence 1: NP_476855.1
• Gene: GluRIA / 38742
• FlyBaseID: FBgn0004619
• Length: 991
• Species: Drosophila melanogaster
• Sequence 2: NP_649012.2
• Gene: Ir75a / 39982
• FlyBaseID: FBgn0036757
• Length: 629
• Species: Drosophila melanogaster
• Alignment Length: 817
• Identity: 146/817 - (17%)
• Similarity: 284/817 - (34%)
• Gaps: 269/817 - (32%)

  Fly   167 GWQSIIYLYDSHDGLLRLQQIYQELKPGNETFRVQMVKRIANVT-MAIEFL-HTLEDLGRFSKKR 229
            |:..:.:.:.|.:.|...||..:.:.|.....:...::.:.|.: :.:.:: ||...|.
  Fly    20 GFIVLFHCWQSDESLKFAQQFMKPIHPILVYHQFVQMRGVLNWSHLELSYMGHTQPTLA------ 78

  Fly   230 IVLDCPAEMAKEIIVQHVRDIKLGRRTYHYLLSGLVMDNHWPSDVVE-FGAINITGFRIVDSNRR 293
            |.:|...:..::::.:..|: ::..:.||:||.|    |....:..: ||..||:    :|::..
  Fly    79 IYVDIKCDQTQDLLEEASRE-QIYNQHYHWLLVG----NQSKLEFYDLFGLFNIS----IDADVS 134

  Fly   294 AVRDFHDSRKRLEPSGQSQSQNAGGPNSLPAISAQAALMYDAV-FVLVEAFN--RILRKKPDQFR 355
            .|::            |.|..|                  |:| :.:.:.:|  :|:
  Fly   135 YVKE------------QIQDNN------------------DSVAYAVHDVYNNGKII-------- 161

  Fly   356 SNHLQRRSHGGSSSSSATGTNESSALLDCNTSKGWVTPWEQGEKISRVLRKVEIDGLSGEIRFDE 420
                     ||  ..:.||::|.|    |:       |:        |.|:..  .||...:..:
  Fly   162 ---------GG--QLNVTGSHEMS----CD-------PF--------VCRRTR--HLSSLQKRSK 194

  Fly   421 DGRRINYTLHVVEMSVNSTLQQVAEWRDDAGLLPLHSHNYASSSRSASASTGDYDRNHTYIVSSL 485
            .|.|...|..|:.::...| |:.....||. |:...|                 ..|.|:|.
  Fly   195 YGNREQLTDVVLRVATVVT-QRPLTLSDDE-LIRFLS-----------------QENDTHID--- 237

  Fly   486 LEEPYLSLKQYTYGESLVGNDRFEGYCKDLADMLAAQLGIKYEIRLVQDGNYGAENQYAPGGWDG 550
                  ||.::.:..:|:..|..  :||               ::.:...::...:...     |
  Fly   238 ------SLARFGFHLTLILRDLL--HCK---------------MKFIFSDSWSKSDVVG-----G 274

  Fly   551 MVGELIRKEADIAISAMTITAERERVIDFSKPFMTLGISIMIKKPVKQTPGVFS----------- 604
            .||.::.:.||:..:....|..|.:.           :|.:|:....::..:|.
  Fly   275 SVGAVVDQTADLTATPSLATEGRLKY-----------LSAIIETGFFRSVCIFRTPHNAGLRGDV 328

  Fly   605 FLNPLSQEIW--ISVILSYVGVSFVLYFVTRFPPYEWRIVRRPQADSTAQQPPGIIGGATLSEPQ 667
            ||.|.|..:|  ...:||.:|   ||.::|.:...: |:.:|.:.|
  Fly   329 FLQPFSPLVWYLFGGVLSLIG---VLLWITFYMECK-RMQKRWRLD------------------- 370

  Fly   668 AHVPPVPPNEFTMLNSFWYSLAAFMQQGCDITPPSIAGRIAAAVWWFFTIILISSYTANLAAFLT 732
             ::|       ::|::|..|..|...|...:.|.|..||:.....:..:.|:.:.||:.:.:.|.
  Fly   371 -YLP-------SLLSTFLISFGAACIQSSSLIPRSAGGRLIYFALFLISFIMYNYYTSVVVSSLL 427

  Fly   733 VERMVAPIKTPEDLTMQTDVNYGTLLYGSTWEFFRRSQIGLHNKMWEYMNANQHHSVHTY----- 792
            ...:.:.|||...|.      ..:|..|.....|.:|          |:|.::...:|.:
  Fly   428 SSPVKSKIKTMRQLA------ESSLTVGLEPLPFTKS----------YLNYSRLPEIHLFIKRKI 476

  Fly   793 -------------DEGIRRVRQSKGKYALLVESPK-----NEYVNARPPCDTMKV---------- 829
                         ::|:.|||.:.| |..:.|:..     ..|..|:..||..:|
  Fly   477 ESQTQNPELWLPAEQGVLRVRDNPG-YVYVFETSSGYAYVERYFTAQEICDLNEVLFRPEQLFYT 540

  Fly   830 --GRNIDTKGFGVATPIGSPLRKRLNEAVLTLKENGELLRIRNKWWFDKTECNLDQETSTPNELS 892
              .||             |..::......|.:.|.|...:.|:.|...|..|.......|   :.
  Fly   541 HLHRN-------------STYKELFRLRFLRILETGVYRKQRSYWVHMKLHCVAQNFVIT---VG 589

  Fly   893 LSNVAGIYYILIGGLLLAVIVAIME-----FFCRNKT 924
            :..||.:..:||...:|.|::.::|     ||.|:.|
  Fly   590 MEYVAPLLLMLICADILVVVILLVELAWKRFFTRHLT 626

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIA	NP_476855.1	PBP1_iGluR_AMPA	41..453	CDD:107375	52/291 (18%)
		ANF_receptor	53..434	CDD:279440	48/272 (18%)
		PBP2_iGluR_AMPA	477..879	CDD:270433	79/449 (18%)
		Lig_chan	612..907	CDD:278489	62/331 (19%)
Ir75a	NP_649012.2	Lig_chan	337..603	CDD:306551	62/329 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462521
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840