DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GluRIA and Ir7g

DIOPT Version :9

Sequence 1:	NP_476855.1	Gene:	GluRIA / 38742	FlyBaseID:	FBgn0004619	Length:	991	Species:	Drosophila melanogaster
Sequence 2:	NP_001368933.1	Gene:	Ir7g / 31694	FlyBaseID:	FBgn0029968	Length:	607	Species:	Drosophila melanogaster

Alignment Length:	438	Identity:	82/438 - (18%)
Similarity:	142/438 - (32%)	Gaps:	133/438 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   550 GMVGELIRKEADIAISAMTITAERERVIDFSKPFMTLGISIMIKKPVKQTPGVFSFLNPLSQEIW 614
            |:.|.|::              |..|.::||..|.  |:...:|.....|..  ..|..|.||..
  Fly   236 GLEGRLLQ--------------ELSRRMNFSIQFS--GLQDQLKNRTTWTEK--QLLQKLVQERI 282

  Fly   615 ISVILSYV--GVSFVLYFVTRFPPYEWRIVRRPQADSTAQQPPGIIGGATLSEPQAHVPPVPPNE 677
            ..:.:.||  .:.:.......||.|..|:|                 |..|.  .||       .
  Fly   283 AHLAIGYVRKRIQYATNLTPVFPHYSNRVV-----------------GCLLL--NAH-------N 321

  Fly   678 FTMLN--SF------WYSLA-AFMQQGC--------------------------DITPPSIAG-R 706
            .|.|.  ||      |..|. :|:...|                          .|.||.... :
  Fly   322 LTSLEIWSFPFQALTWICLVFSFLSISCLALLHXRGAGDRLALVLAVYAASLGLPIDPPERPSLQ 386

  Fly   707 IAAAVWWFFTIILISSYTANLAAFLTVERMVAPIKTPEDLTMQTDVNYGTLLYGSTWEFFR---- 767
            :..|.|..|.:|:.|.|:|.|...|   |.....:.|.:|...|..:|..::..:|.:..|
  Fly   387 LLFASWLIFGLIVRSMYSALLFFIL---RYHLHQRLPGNLQDLTHGDYAAVMGRTTLQDLREVPS 448

  Fly   768 -RSQIGLHNKMWEYMNANQHHSVHTYDEGIRRVRQSKGKYAL---LVESPKNEYVNARP------ 822
             :..:||.:.:  ..:..:...:.|.|.  ..:|:..|.:.|   |:......::..|.
  Fly   449 LQDLLGLKSVI--VTSEREEEVLRTLDR--CTLREGAGSHPLFFGLISQDALLHLTQRGHRAGAY 509

  Fly   823 ---PCDTMKVGRNIDTKGFGVATPIGSPLRKRLNEAVLTLKENGELLRIRNKW--------WFDK 876
               |.|.::       :...:.....|.|...|:..|::::..|    :.:.|        :|..
  Fly   510 HIIPQDVLE-------QQLAIYLQKHSHLASHLDHLVMSIRSVG----LVHHWAGQMASERYFRS 563

  Fly   877 TECNLDQETSTPNELSLSNVAGIYYILIGGL-LLAVIVAIMEFFCRNK 923
            .....::....|:..::       |||..|| ||:::|.|.|.....:
  Fly   564 RFLYREKRIRQPDLWAV-------YILTAGLYLLSLVVFICELLASRR 604

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GluRIA	NP_476855.1	PBP1_iGluR_AMPA	41..453	CDD:107375
		ANF_receptor	53..434	CDD:279440
		PBP2_iGluR_AMPA	477..879	CDD:270433	71/391 (18%)
		Lig_chan	612..907	CDD:278489	61/357 (17%)
Ir7g	NP_001368933.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462555
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840