Protein Alignment GluRIA and Ir7b

DIOPT Version :9

• Sequence 1: NP_476855.1
• Gene: GluRIA / 38742
• FlyBaseID: FBgn0004619
• Length: 991
• Species: Drosophila melanogaster
• Sequence 2: NP_572410.2
• Gene: Ir7b / 31690
• FlyBaseID: FBgn0029965
• Length: 655
• Species: Drosophila melanogaster
• Alignment Length: 751
• Identity: 127/751 - (16%)
• Similarity: 217/751 - (28%)
• Gaps: 315/751 - (41%)

  Fly   367 SSSSSATGTNESSALLDCNTSKGWVTPWEQGEKISRVLRKVEIDGLSGEIRF-----------DE 420
            |..|....|.|||            :.|:..|.:::|:...|:.      ||           ..
  Fly     9 SCCSLVASTMESS------------SDWDLAEALAQVVANSEMG------RFKTLYIYTHTNSQS 55

  Fly   421 DGRRINYTLHVVEMSVNST-------LQQVAEWRD---------DAGLLPLHSHNYASSSRSASA 469
            .|..:...|..|.|.|.:.       |||..|::.         |.  ||..|..||....:
  Fly    56 TGGHLEELLDQVLMIVPNNLQARRLLLQQSMEYKPYVHAVLALVDG--LPSLSAIYARIRAT--- 115

  Fly   470 STGDYDRNHTYIVSSLLEEPYLSLKQYTYGESLVGNDRF-------------------------- 508
                .|.:||.|        |:|:....|||.:....||
  Fly   116 ----QDLSHTLI--------YMSMPTDAYGEEMQATLRFLWRLSVLNVGVVLRPPGDHILMVSYF 168

  Fly   509 -----EGYCKDLA-----------------DMLAAQLGIKYEIRLV----QDGNYGAENQYAPGG 547
                 .| |:.::                 |...::||..|...|.    :|..|........|.
  Fly   169 PFSALHG-CQVISANVVNRYQVGTKRWASQDYFPSKLGNFYGCLLTCATWEDMPYLVWRPDGSGS 232

  Fly   548 WDGMVGELIRKEAD-IAISAMTITAERERVI------------------DFS------KP----- 582
            :.|:.|.|::..|: :..:.......:|.|:                  |||      ||
  Fly   233 FVGIEGALLQFMAENLNFTVGLYWMNKEEVLATFDESGRIFDEIFGHHADFSLGGFHFKPSAGSE 297

  Fly   583 ---------FMTLGISIMIKKPVKQTPGVFSFLN-PLSQEIWISVILSYVGVSFVLYFVTRFPPY 637
                     ||:   .||:...::.....:..|: |.:..:|.::.|..:....:|..:.|
  Fly   298 IPYSQSTYYFMS---HIMLVTNLQSAYSAYEKLSFPFTPLLWRAIGLVLILACLLLMLLVR---- 355

  Fly   638 EWRIVRRPQADSTAQQPPGIIGGATLSEPQAHVPPVPPNEF------TM---LNSFWYSLAAFMQ 693
             ||                            |...:|.|.:      ||   |...|
  Fly   356 -WR----------------------------HHHELPRNPYYELLVLTMGGNLEDRW-------- 383

  Fly   694 QGCDITPPSIAGRIAAAVWWFFTIILISSYTANLAAFLTVERMVAPIKTPEDLTMQ------TDV 752
                 .|.....|:....|.|.|::|.|.|.:.:...|..:....|.:|..::..|      .:|
  Fly   384 -----VPQRFPSRLVLLTWLFATLVLRSGYQSGMYQLLRQDTQRNPPQTISEVLAQHFTIQLAEV 443

  Fly   753 NYGTLLYGSTWEFFRRSQIGLHNKMWEYMNANQHHSVHTYDEGIRRVRQSKGKYALLVESPKNEY 817
            |...:|         .|...|..:...|:..::..|       ...:.|..|..|.:......||
  Fly   444 NEARIL---------ASLPELRPEQLVYLEGSELQS-------FPALAQQSGSSARVAILTPYEY 492

  Fly   818 VNARPPCDTMKVGRNIDTKGFGVATPIGSPLRKRLN---EAVLT------LKENGELLRIRNK-- 871
                                ||....: .|:.:||:   |.:.|      ::.:..|:.:.||
  Fly   493 --------------------FGYFRKV-HPMSRRLHLVRERIYTQQLAFYVRRHSHLVGVLNKQI 536

  Fly   872 ----------WWFDK--------------------------------TECNLDQETS--TPNELS 892
                      .|..:                                :|...||:.:  ..|.||
  Fly   537 QHAHTHGFLEHWTRQYVSAVDEKDESVARIASTSYSTLDGIDGDPSLSESEEDQQVAPVRQNVLS 601

  Fly   893 LSNVAGIYYILIGGLLLAVIVAIMEFFCRNKTPQLK 928
            :..:|.::::::...|.||:|.::|..    .|::|
  Fly   602 MRELAALFWLILWANLGAVVVFVLELL----LPRIK 633

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIA	NP_476855.1	PBP1_iGluR_AMPA	41..453	CDD:107375	22/112 (20%)
		ANF_receptor	53..434	CDD:279440	15/77 (19%)
		PBP2_iGluR_AMPA	477..879	CDD:270433	85/561 (15%)
		Lig_chan	612..907	CDD:278489	55/364 (15%)
Ir7b	NP_572410.2	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462568
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840