Protein Alignment GluRIA and W02A2.5

DIOPT Version :9

• Sequence 1: NP_476855.1
• Gene: GluRIA / 38742
• FlyBaseID: FBgn0004619
• Length: 991
• Species: Drosophila melanogaster
• Sequence 2: NP_502564.2
• Gene: W02A2.5 / 189098
• WormBaseID: WBGene00012190
• Length: 487
• Species: Caenorhabditis elegans
• Alignment Length: 479
• Identity: 89/479 - (18%)
• Similarity: 164/479 - (34%)
• Gaps: 155/479 - (32%)

  Fly   508 FEGYCKDLADMLAAQLGIKYEI------RLVQDGNYGAENQYAPGGWDGMVGELIRKEADIAISA 566
            |.|:..::..|:...|  |:||      .:|...::|...:  .|.|.|::|.|....||.....
 Worm    36 FPGWTMEVLKMITDSL--KWEIIPVVTPTIVGGLDWGTLQK--NGTWSGVLGYLQNGTADAVALM 96

  Fly   567 MTITAERERVIDFSKPFMTLGISIMIKKPVKQTPG--VFSFLNPLSQEIWISVILSYV------- 622
            ...|..|....::|.| :|....:.:.:...:|.|  :::...|.|.|:|:.::.|.|
 Worm    97 YQKTDTRNEYFEYSYP-VTNVQPVFVARKKTETLGSVLWNAFKPFSVEVWLCLLASLVLNLLIMI 160

  Fly   623 ---GVSFVLYFVTRFPPYE--WRIVRRPQADSTAQQPPGIIGGATLSEPQAHVPPVPPNEFTMLN 682
               |:.|.|.|.:||.|:|  |.:|:. |.|..:.                             :
 Worm   161 AISGIEFKLLFRSRFRPWEMLWHVVQL-QLDEKSD-----------------------------D 195

  Fly   683 SFWYSLA--------AFMQQGCDITPPSIAGRIAAAVWWFFTIILISSYTANLAAFLTVERMVAP 739
            ..:|:|:        |.:|.|                      |||..|...|...|.......|
 Worm   196 MLFYTLSGNIVLFVFALLQSG----------------------ILIEVYKGMLLTALITSNGDNP 238

  Fly   740 IKTPED-LTMQTDVNYG-TLLYGSTWEFFRRSQIGLHNKMWEYMNANQHHSVHTYDEGIRRVRQS 802
            ....:: :.:..:..|. |..|...|.|.            :..:::|.|.|     .:|....|
 Worm   239 FANADEMIKLIGEKKYHLTTNYMGNWYFD------------DLQHSDQQHFV-----SLRAATAS 286

  Fly   803 -----------------KGKYALLVESPKNEYVNARPPCDTMKVGRN--------IDTKGF-GVA 841
                             .|||...::........::..|:.:.|...        :.||.| |:|
 Worm   287 NPVIPAASVSAALDLVDSGKYIYPIQQDSLAMQMSKERCNYVYVSDGMPQVSSFFVFTKNFSGIA 351

  Fly   842 ---TPIGSPLRKRLNEAVLTLKENGELLRIRNKWWFDK------TECNLDQETST--PNELSLSN 895
               |.|      .:|:|.:.        |..||::.:.      .:|.:.:.|::  ...|.:.:
 Worm   352 EFNTQI------IMNQAFIQ--------RTFNKYFNEGFKLGFIPKCEVTEPTASDATKPLDIES 402

  Fly   896 VAGIYYILIGGLLLAVIVAIMEFF 919
            |.|::.|...|:..:::|.:.|.:
 Worm   403 VIGVFTIGALGVAASLMVFVFEIY 426

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIA	NP_476855.1	PBP1_iGluR_AMPA	41..453	CDD:107375
		ANF_receptor	53..434	CDD:279440
		PBP2_iGluR_AMPA	477..879	CDD:270433	80/435 (18%)
		Lig_chan	612..907	CDD:278489	61/353 (17%)
W02A2.5	NP_502564.2	Lig_chan-Glu_bd	<36..86	CDD:214911	13/53 (25%)
		Periplasmic_Binding_Protein_Type_2	<74..>124	CDD:304360	12/52 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810