Protein Alignment GluRIA and T25E4.2

DIOPT Version :9

• Sequence 1: NP_476855.1
• Gene: GluRIA / 38742
• FlyBaseID: FBgn0004619
• Length: 991
• Species: Drosophila melanogaster
• Sequence 2: NP_001364710.1
• Gene: T25E4.2 / 188897
• WormBaseID: WBGene00020804
• Length: 455
• Species: Caenorhabditis elegans
• Alignment Length: 507
• Identity: 88/507 - (17%)
• Similarity: 154/507 - (30%)
• Gaps: 194/507 - (38%)

  Fly   489 PYLSLKQYTYG----------ESLVGNDRFEGYCKDLADMLAAQLGIKYEIRLVQDGNYGAENQY 543
            ||:||..|.:.          |.|  |..|: .....|.::.....|:..|.:|.:|:
 Worm    18 PYVSLSNYCWSFNCPKPGAEVEFL--NMTFQ-LMNSTATIVQIDADIEQSIDMVSNGS------- 72

  Fly   544 APGGWDGMVGELIRKEADIAISAMTITAERERVIDFSKP--FMTLGISIMIKKPVKQTP--GVFS 604
                            |||.:.:...|.:|.:.:||:.|  |:..|..      |::.|  .|..
 Worm    73 ----------------ADITLVSARQTLDRMKKVDFTTPIGFVYYGYL------VREIPELAVAD 115

  Fly   605 FLNPLSQEIWISVILSY-VGVSFVLYFVTRFPPYEWRIVRRPQADSTAQQPPGIIGGATLSEPQA 668
            ::..|.....:::::|: :.:..:||.      |.|                 |.|....|
 Worm   116 YIMRLFDYDTLAILISFGLIIGALLYL------YTW-----------------IFGLRVRS---- 153

  Fly   669 HVPPVPPNEFTMLNSFWYSLAAFMQQGCDITPPSIAGRIAAAVWWFFTIILISSYTANLAAFLTV 733
                       :|:..:.|.:..:.|........|...:....|....:::|:.|.|.|.:||.:
 Worm   154 -----------LLDWMFISCSGIIHQFMFRISSPICALVLIGFWLLCCLVIITYYEAKLKSFLLL 207

  Fly   734 ERMVAPIKTPEDLTMQTDVNYGTLLYGSTWEFFRRSQIGLHNKMWEYMNANQHHSVHTYDEGIRR 798
            ..                 :.||:.                               :|.| |:..
 Worm   208 SH-----------------HRGTIF-------------------------------NTLD-GVLE 223

  Fly   799 VRQSKGKYALLVESPKNEYVNARP-PC---DTMK-----VGRNIDTK---------GFG------ 839
            ..:.||...::.|.....|:...| .|   |.:|     :|.:.|..         ||.
 Worm   224 AAEHKGWTLVIQERGYTPYLYCNPSQCARLDRLKSRINFIGADDDANLLLGQDKHVGFSALASDL 288

  Fly   840 ----------------VATPIGSP-------------LRKRLNEAVLTLKENGELLRIRNKWWFD 875
                            |...|.:|             ||::.|.||...|.....:|.|....|.
 Worm   289 AETDITYFDYHSKILFVRDKIMAPEYLAYAVNKNVKGLREKFNRAVAYTKSGYGTVRSRYIASFP 353

  Fly   876 KTECNLDQETSTPNELSLSNVAGIY---YILIGGLLLAVIVAIMEFFCRNKT 924
            ... ::..::.|...|..|:...:|   :|..|   :|:||.|:|......|
 Worm   354 SYN-SVTSQSQTITVLQTSHFIQLYKFCFIFYG---IAIIVFILEIIFHRMT 401

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIA	NP_476855.1	PBP1_iGluR_AMPA	41..453	CDD:107375
		ANF_receptor	53..434	CDD:279440
		PBP2_iGluR_AMPA	477..879	CDD:270433	76/457 (17%)
		Lig_chan	612..907	CDD:278489	54/351 (15%)
T25E4.2	NP_001364710.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900