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Protein Alignment GluRIA and glr-8

DIOPT Version :10

Sequence 1:	NP_476855.1	Gene:	GluRIA / 38742	FlyBaseID:	FBgn0004619	Length:	991	Species:	Drosophila melanogaster
Sequence 2:	NP_001368711.1	Gene:	glr-8 / 180924	WormBaseID:	WBGene00001619	Length:	547	Species:	Caenorhabditis elegans

Alignment Length:	571	Identity:	131/571 - (22%)
Similarity:	208/571 - (36%)	Gaps:	140/571 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   455 LHSHNYASSSRSASASTGDYDRNHTY-----------------IVSSLLEEPYLSLKQYT----- 497
            |.|.|...:....::.|.||...:|.                 :|...:|.||::...::
Worm    23 LESINEKVAHPPQTSLTSDYGDAYTLSNEKHFSLSEMKGRTLKMVVPAIEPPYVNYVNFSDAAVT 87

  Fly   498 ---YGESLVGNDRFEGYCKDLADMLAAQLGIKYEIRLVQDGNYGAENQYAPGGWDGMVGELIRKE 559
               ||..:|         .::...:..:|.:.|||.......:|   :|..|.|.|..|:|:|.|
Worm    88 DKGYGPGVV---------MEILKEIGKRLNLTYEILPALGSTWG---EYLNGSWTGAFGQLVRGE 140

  Fly   560 ADIAISAMTITAERERVIDFSKPFMTLGISIMIKKPVK-QTPGVFSFLNPLSQEIWI---SVILS 620
            .|:......:..:|..:.|.:.||......|||:.|.| :...:.....|.|.|:|:   :|||
Worm   141 VDLLAGGAIMEYDRSVIADLTYPFQFEPTGIMIRSPEKYEDDTLLIVTEPFSWEVWVITAAVIL- 204

  Fly   621 YVGVSFVLYFVTRFPPYEWRIVRRPQADSTAQQPPGIIGGATLSEPQAHVPPVPPNEFTMLNSFW 685
               :|.|::.|..      .|:|:...:.|.                           |...|.|
Worm   205 ---ISGVIFLVMT------NIIRKVYEEMTV---------------------------TPFESIW 233

  Fly   686 YSLAAFMQQGCDITPPSIAGRIAAAVWWFFTIILISSYTANLAAFLTVERMVAPIKTPEDLT--- 747
            ...:.|:|||....|.|.:.|:..|:||..:|.|.:::|.:|.|...|::...|.:..:.|.
Worm   234 VFFSIFVQQGLPEQPRSWSCRVLVALWWLASITLSATFTGSLVALFAVDKTNVPFQNIDQLVRLV 298

  Fly   748 ------MQTDVNYGTLLYGSTWEFFRRSQIGLHNKMWEYMNANQHHSVHTYDEGIRR----VRQS 802
                  :..|.|..|     ..|...||::.::..:|..|..|  |.| .|..||.|    ||.:
Worm   299 KQGKFEIVMDENSFT-----RTEMIARSKLPVYRDLWHEMIVN--HKV-KYVNGIARGVAFVRAN 355

  Fly   803 KGKYALLVESPK---NEYVNARPPCDTMKVGRNIDTKGFGVATPIGSPLRKR------LNEAVLT 858
            .| ||||  .|.   |.|  |...|..:.....|      :...:..||.|.      .:..:..
Worm   356 PG-YALL--GPMATLNFY--AYSDCKVILFNDGI------LPVYLSIPLVKNSIYSPYFSTKIRE 409

  Fly   859 LKENGELLRIRNKWWFDK---------TECNLDQETSTPNE-LSLSNVAGIYYILIG--GLLLAV 911
            :.|.|    ...||..|.         .|||  ..|..|.. |.|....|.:::.:|  ||.||:
Worm   410 MVERG----FTQKWIADYRSYVAMQKINECN--STTIGPKSYLDLKRAQGAFWVFLGGAGLGLAL 468

  Fly   912 IVA--IMEFFCRNKTPQLKSPGSNGSAGGVPGMLASSTYQRDSLSDAIMHS 960
            .|.  |.:||....|...|:.........|...:|.::...| :.|.::.|
Worm   469 FVGEFIFKFFREKMTKHTKTTTVPPEVATVSANVAENSTSLD-IPDEVLPS 518

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.