DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment axed and Btbd1

DIOPT Version :9

Sequence 1:	NP_001356975.1	Gene:	axed / 38741	FlyBaseID:	FBgn0035708	Length:	582	Species:	Drosophila melanogaster
Sequence 2:	NP_666305.2	Gene:	Btbd1 / 83962	MGIID:	1933765	Length:	488	Species:	Mus musculus

Alignment Length:	221	Identity:	56/221 - (25%)
Similarity:	81/221 - (36%)	Gaps:	57/221 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   283 QTVITTQETGQQLARKKATKAKAA------AKQLAAAKASQSTENGAEGDGAQQNLIPNPNPFTT 341
            :||:||..|    |:|.|..|..|      .|.|.|..|....        .|..|...|.
Mouse   152 ETVMTTLYT----AKKYAVPALEAHCVEFLTKHLRADNAFMLL--------TQARLFDEPQ---- 200

  Fly   342 EDYGVALLHNTLQLIDMHAELQLSMPEISDLRFEELETLVKRDTLQLRSEVTLFECLATWSLAEC 406
                  |....|..||......:|....:|:..:.|..:::||||.:| |..||..:..|:.|||
Mouse   201 ------LASLCLDTIDKSTVDAISAEGFTDIDIDTLCAVLERDTLSIR-ESRLFGAIVRWAEAEC 258

  Fly   407 ARKHIDATPENRRTVLGPLCLTPRYLRMTASEFRRCCERLELLPPTEISLITDALDGKKLKNLTD 471
            .|:.:..|..|::.|||......|:..||..||        ...|.:..:::|
Mouse   259 QRQQLAVTFGNKQKVLGKALSLIRFPLMTIEEF--------AAGPAQSGILSD------------ 303

  Fly   472 QQAELLEKF------RQPRAEYARMP 491
              .|::..|      .:||.||...|
Mouse   304 --REVVNLFLHFTVNPKPRVEYIDRP 327

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
axed	NP_001356975.1	BTB	<192..258	CDD:197585
axed	NP_001356975.1	BACK	<354..423	CDD:355779	21/68 (31%)
Btbd1	NP_666305.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..42
		BTB	68..177	CDD:279045	10/28 (36%)
		BTB	94..181	CDD:197585	11/32 (34%)
		BACK	193..292	CDD:197943	32/117 (27%)
		PHR	340..486	CDD:285277
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2075
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810