Protein Alignment axed and Btbd6

DIOPT Version :10

• Sequence 1: NP_001356975.1
• Gene: axed / 38741
• FlyBaseID: FBgn0035708
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: NP_001071151.2
• Gene: Btbd6 / 690367
• RGDID: 1597323
• Length: 539
• Species: Rattus norvegicus
• Alignment Length: 528
• Identity: 113/528 - (21%)
• Similarity: 175/528 - (33%)
• Gaps: 164/528 - (31%)

  Fly   122 APAPSAP-PAHMMPPAYARGQTNIYTGVPIIVNPYIDFIVVNGDDRYMIRCERKSVLERSVELAK 185
            ||||..| ||   ||            :|...||...    |....:....||.:::..: ||..
  Rat    93 APAPLPPLPA---PP------------LPDNNNPESP----NWQSFHPTLRERNALMFNN-ELMA 137

  Fly   186 LIH---AGPNSGRKSDNHFQILNVDKNDFELIVRYMEKHFIPYRDHKHLLKILELSDRFNVPDLI 247
            .:|   ....:.|:...|..:|.|..:.|         :.:.|.|      :.|:....::||
  Rat   138 DVHFIVGALGAARRVPAHKYVLAVGSSVF---------YAMFYGD------LAEVKSEIHIPD-- 185

  Fly   248 IYCIRELDLRISSATALDIFKALWFYQGIALTNQHQTVITTQETGQQLARKKATKAKAAAKQL-- 310
                      :..|..|.:.|.::..:   :..:..||:.|              ..||.|.:
  Rat   186 ----------VEPAAFLVLLKYMYSDE---IDLEADTVLAT--------------LYAAKKYIVP 223

  Fly   311 AAAKASQS-TENGAEGDGA-----QQNLIPNPNPFTTEDYGVALLHNTLQLIDMHAELQLSMPEI 369
            |.|||..: .|...|...|     |..|...|.          |.....::||..||:.|.....
  Rat   224 ALAKACVNFLETSLEAKNACVLLSQSRLFEEPE----------LTQRCWEVIDAQAEMALRSEGF 278

  Fly   370 SDLRFEELETLVKRDTLQLRSEVTLFECLATWSLAECARKHIDATPENRRTVLGPLCLTPRYLRM 434
            .::..:.||.:|.|:.|..: |..:||.:..|:.|||.|:.:..||.|:|.|||......|...|
  Rat   279 CEIDRQTLEIIVTREALNTK-EAVVFEAVLNWAEAECKRQGLPVTPHNKRHVLGRALYLVRIPTM 342

  Fly   435 TASEFRRCCERLELL-----------------PPTEISLITDALDGKKLKNLTDQQAELLEK--F 480
            |..||.....:.::|                 ||.:..|       .|.|.|..|:....:.  :
  Rat   343 TLEEFANGPAQSDILTLEETHNIFLWYTAAKKPPLDFPL-------TKRKGLVPQRCHRFQSSAY 400

  Fly   481 RQPRAEY-----------------ARMPVHLSDRSSPKNYPKKMRLAHEG--------RPTEDG- 519
            |..:..|                 |.:.::.|. |....|..|:.|...|        :...||
  Rat   401 RSNQWRYRGRCDSIQFAVDRRVFIAGLGLYGSS-SGKAEYSVKIELKRLGMVLAQNLTKFVSDGS 464

  Fly   520 -----CW----EKVGMNCLRIFVCIFDXSEQS-DGEEEEEEEDGDDEEE--------DDGSDEEN 566
                 .|    .:|..:.......:.|.||.| .|:|      |..|.:        ...||..|
  Rat   465 SNTFPVWFEHPVQVEQDTFYTASAVLDGSELSYFGQE------GMTEVQCGKVAFQFQCSSDSTN 523

  Fly   567 GNGNRAGR 574
            |.|.:.|:
  Rat   524 GTGVQGGQ 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
axed	NP_001356975.1	BACK	<354..423	CDD:475122	23/68 (34%)
Btbd6	NP_001071151.2	BTB_POZ_BTBD6	129..237	CDD:349658	27/152 (18%)
		BACK_BTBD6	237..331	CDD:350600	29/104 (28%)
		PHR	393..538	CDD:462339	27/146 (18%)