DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment axed and Btbd19

DIOPT Version :9

Sequence 1:	NP_001356975.1	Gene:	axed / 38741	FlyBaseID:	FBgn0035708	Length:	582	Species:	Drosophila melanogaster
Sequence 2:	XP_038967447.1	Gene:	Btbd19 / 100361234	RGDID:	2320529	Length:	399	Species:	Rattus norvegicus

Alignment Length:	182	Identity:	35/182 - (19%)
Similarity:	64/182 - (35%)	Gaps:	71/182 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly   134 PPAYARGQTNIYTGV--PIIVNP-YIDFIVVNGDDRYMI---------RC---ER---------- 173
            |....|||...::..  .:|.|| |.|...|.|.:|..:         ||   :|
  Rat     4 PGLVVRGQAAPFSTALRSLINNPRYSDICFVVGQERQEVFAHRCLLACRCNFFQRLLGPGIPSPV 68

  Fly   174 ----------KSVLE----RSVELAKLIHAGPN---SGRKSDN-------HFQILNVDKNDFELI 214
                      .:|||    .||:|.:...:.|:   .||::::       .|..||...:
  Rat    69 VLSTVPAEAFLAVLEFLYTNSVKLHRYSVSLPSRGLGGREAEDARGAGETPFCSLNHSHS----- 128

  Fly   215 VRYMEKHFIPYRDHKHLLKILELSDRFNVPDLIIYC--------IRELDLRI 258
                     |:.|...:|::|..:..:.:.:|..:|        ::.||:.:
  Rat   129 ---------PHPDPVQVLEVLTAAVEYGLEELREFCPQLCLEFVVKVLDVEL 171

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
axed	NP_001356975.1	BTB	<192..258	CDD:197585	13/83 (16%)
axed	NP_001356975.1	BACK	<354..423	CDD:355779
Btbd19	XP_038967447.1	BTB_POZ_BTBD19	15..163	CDD:349603	29/161 (18%)
Btbd19	XP_038967447.1	BACK_BTBD19	168..240	CDD:350569	1/4 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166350760
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930