Protein Alignment Rexo5 and RNH70

DIOPT Version :10

• Sequence 1: NP_648050.1
• Gene: Rexo5 / 38740
• FlyBaseID: FBgn0286051
• Length: 681
• Species: Drosophila melanogaster
• Sequence 2: NP_011792.1
• Gene: RNH70 / 853193
• SGDID: S000003508
• Length: 553
• Species: Saccharomyces cerevisiae
• Alignment Length: 605
• Identity: 151/605 - (24%)
• Similarity: 247/605 - (40%)
• Gaps: 149/605 - (24%)

  Fly    97 EEPVNKKIRNYDAGGDSLPLEIGSLSEDQYNQLSAELRRRKRELENVP--ALRLREMGQRASLET 159
            |.|....:.:...|.....|...|:.||.:..:.:|:.:.|::.:..|  ...|:.:.::.
Yeast     4 EGPDTNFVSDLALGSKKRRLSKTSVQEDDHTNVVSEVNKNKKKKKAKPMTCTLLKSVVEKG---- 64

  Fly   160 PQDARTPIFLTDIQNLLMCALIGQ-KSPCRPDRWCSVEKWLSLSHSVVVILEGLSLYHYLSNETQ 223
                   |.:.|::::....|..: .||    :|..:....||...:|:.:.||....:.:.:..
Yeast    65 -------IGIKDVRDMTQYLLQAENNSP----KWIDICNRSSLQKMIVLFIPGLQPDDFENGKNT 118

  Fly   224 FEATNRIFSTKLEMI----------LPPQEEGQKIIDEIAKIPLTNAQARRLIDEHGSLESAVEL 278
            |   |.|.....:.|          .|....|.|:
Yeast   119 F---NEISDDNFKYIPGEIASTFHTFPVMAPGSKM------------------------------ 150

  Fly   279 NKDPTLF--VKTIFPIESSKSES----DDMHEDDKFPRTKLLLSALQMVDEGYPIPLQGELHTRF 337
                |||  ..:...:..||.|.    .::.:..|.....|:||..|:|...||:. .|:  |.|
Yeast   151 ----TLFSPYNSFINVGLSKMEKINKLKELQKKKKITINDLVLSEQQLVANDYPLD-SGD--TNF 208

  Fly   338 -----QNFKFTKDLYAPVTNRSPMFGVDCEMCHTEAGCNELTRISIVNENYETVYETLVLPNNRI 397
                 |...||.       ..|.:|.:|||||.:|.|. .|||||:||.:.|.:||.||.|:..|
Yeast   209 DTDWVQTVDFTH-------GGSHIFALDCEMCLSEQGL-VLTRISLVNFDNEVIYEELVKPDVPI 265

  Fly   398 TDYLTQYSGITAE-IMEQVTKRLDVVQKEVSELLPPDAILVGQSLNSDLNAMKMMHPYVIDTSVC 461
            .||||:|||||.| :.....|.|..|||::.:::....||:|.||.:||..||:.||.|:||::.
Yeast   266 VDYLTRYSGITEEKLTVGAKKTLREVQKDLLKIISRSDILIGHSLQNDLKVMKLKHPLVVDTAII 330

  Fly   462 FNTSGVRRRKTKLKDLAKTFLQEIIQENIDGHDSIEDSRATLKLVKKKLANSIEFGDQILTQHKQ 526
            ::.......|..||.|::|||.:.||..  .|||:||:||.|:|.|.|:.|.:.||..|.|:
Yeast   331 YHHKAGDPFKPSLKYLSETFLNKSIQNG--EHDSVEDARACLELTKLKILNGLAFGIGINTE--- 390

  Fly   527 LQELANASSGDTISNNLFAHVAKRDKRTAIV--------TVGELQPRLKEVIEKAGEAAPKDQST 583
                           |||..:.:.:.:|.::        |..:.:.:|...:|        |..|
Yeast   391 ---------------NLFTKLHRFEVKTVLLNDMIIKNHTEDDSKGQLIRCVE--------DDET 432

  Fly   584 SVHVHE---------VSTAK--EAIRKVNEVALENALTIANLRVPEQDFILDSAQRSVAKLDKTI 637
            ..|:||         |...|  |..|..|             :.|.::.....|...:..:.:.:
Yeast   433 WTHIHENLNKDVKLIVGRIKNLERSRNYN-------------KKPRKETPSFDASMVLHDIGQHL 484

  Fly   638 DRLWKSVAHNGLFLVIMGGS 657
            .:|::: |..|..::||.|:
Yeast   485 TQLYEN-ATPGTMILIMSGT 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rexo5	NP_648050.1	REX1_like	357..507	CDD:99848	69/150 (46%)
RNH70	NP_011792.1	REX1_like	226..374	CDD:99848	69/150 (46%)