Protein Alignment Rexo5 and ISG20L2

DIOPT Version :10

• Sequence 1: NP_648050.1
• Gene: Rexo5 / 38740
• FlyBaseID: FBgn0286051
• Length: 681
• Species: Drosophila melanogaster
• Sequence 2: NP_001290024.1
• Gene: ISG20L2 / 81875
• HGNCID: 25745
• Length: 353
• Species: Homo sapiens
• Alignment Length: 284
• Identity: 75/284 - (26%)
• Similarity: 124/284 - (43%)
• Gaps: 57/284 - (20%)

  Fly   245 GQKIIDEIAKIPLTNAQARRL------IDEHGSLESAV-ELNKDPTLFVKTIFPIESSKSESDDM 302
            ||.:..:.|...||.|.:::.      :|..|..:||: ::|..||...|.    .|.|..|...
Human    89 GQPLDKKAAVSWLTPAPSKKADSVAAKVDLLGEFQSALPKINSHPTRSQKK----SSQKKSSKKN 149

  Fly   303 HEDDKFPRTKLLLSALQMVDEGYPIPLQGELHTRFQNFKFTKDLYAPVTNRSP--MFGVDCEMCH 365
            |.....|:...                  :.|        :::..:..:.:.|  |..:||||..
Human   150 HPQKNAPQNST------------------QAH--------SENKCSGASQKLPRKMVAIDCEMVG 188

  Fly   366 T--EAGCNELTRISIVNENYETVYETLVLPNNRITDYLTQYSGITAEIMEQVTKRLDVVQKEVSE 428
            |  :...:.|.|.||||.|.:.:|:..:||...|.||.|::|||..:.|...|. ..:.:.::.:
Human   189 TGPKGHVSSLARCSIVNYNGDVLYDEYILPPCHIVDYRTRWSGIRKQHMVNATP-FKIARGQILK 252

  Fly   429 LLPPDAILVGQSLNSDLNAMKMMHPYVIDTSVCFNTSGV--RRRKT--------KLKDLAKTFLQ 483
            :| ...|:||.::::|..|::..||    .|:..:||.:  ..||.        .||.|.|..|.
Human   253 IL-TGKIVVGHAIHNDFKALQYFHP----KSLTRDTSHIPPLNRKADCPENATMSLKHLTKKLLN 312

  Fly   484 EIIQENIDGHDSIEDSRATLKLVK 507
            ..||....||.|:||::||::|.|
Human   313 RDIQVGKSGHSSVEDAQATMELYK 336

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rexo5	NP_648050.1	REX1_like	357..507	CDD:99848	52/161 (32%)
ISG20L2	NP_001290024.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..93		2/3 (67%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	125..172		11/76 (14%)
		ISG20	180..336	CDD:99852	52/161 (32%)