Protein Alignment Rexo5 and C05C8.5

DIOPT Version :10

• Sequence 1: NP_648050.1
• Gene: Rexo5 / 38740
• FlyBaseID: FBgn0286051
• Length: 681
• Species: Drosophila melanogaster
• Sequence 2: NP_504838.1
• Gene: C05C8.5 / 179116
• WormBaseID: WBGene00015462
• Length: 594
• Species: Caenorhabditis elegans
• Alignment Length: 714
• Identity: 191/714 - (26%)
• Similarity: 287/714 - (40%)
• Gaps: 206/714 - (28%)

  Fly    39 ELAKKRDAEVEVEEKSTAKAEDGDDGFIVVGSKRKPRNRRQNNELEADSQTAPGTS--DPEEPVN 101
            ||.|...:|:|...||..:||..    ....:||:   |..::|....|   |.||  ||.:|
 Worm     5 ELRKSLKSEIENLFKSPEQAEHE----FQCATKRR---RLTSSEKPTKS---PSTSSDDPSKP-- 57

  Fly   102 KKIRNYDAGGDSLPLEIGSLSEDQYNQLSAELRRRKRELENVPALRLREMGQRASLET-PQDART 165
                       .|.|.:..|.:                            |.|...|| .|....
 Worm    58 -----------KLELRLSRLGD----------------------------GHRLDCETLAQFIHF 83

  Fly   166 PIFLTDIQNLLMCALIGQKSPCRPDRWCSVEKWLSLSHSVVVILEGLSLYHYLSNETQFEATNRI 230
            .||.:.:|              :|       :|:||||...| |:.|.:...:.::. |..||..
 Worm    84 SIFGSSLQ--------------KP-------RWVSLSHHRNV-LQNLVVRVNVDDDF-FTTTNLS 125

  Fly   231 FSTK------LEMILPPQEEGQKIIDEIAKIPLTNAQARRLIDEHGSLESAVELNKDPTLFVKTI 289
            |.::      :|:.....:.| ...:.|.::.||       |.|        ::.:...:..||.
 Worm   126 FLSEFFEKQWIELDSDVSDRG-LFWNSIMQVRLT-------IQE--------QIRRKSVIMQKTY 174

  Fly   290 FPIESSKSESDDMHEDDKFPRTKLLLSALQMVDEGYPIPLQGELHTRFQNFKFTKDLYAPVTNRS 354
                    :.|..|:...|     :|:..|:....||.|  ||     :....||..|..::..|
 Worm   175 --------DRDGKHDKSHF-----VLTTEQLAQRRYPFP--GE-----EGVVPTKQGYKKISASS 219

  Fly   355 PMFGVDCEMCHTEAGCNELTRISIVNENYETVYETLVLPNNRITDYLTQYSGITAEIMEQVTKRL 419
            |||.||||||.|:....||||||||:|...|:.:|||.|..|||||:|::||||.::||.||..|
 Worm   220 PMFSVDCEMCETDVANRELTRISIVDEFENTILDTLVKPEGRITDYVTRWSGITPDMMEGVTTTL 284

  Fly   420 DVVQKEVSELLPPDAILVGQSLNSDLNAMKMMHPYVIDTSVCFN-TSGVRRRKTKLKDLAKTFLQ 483
            ..|||.:..||||||||||.||..||.||||.||:.:|.....| |:.....:..||:|.:.||.
 Worm   285 GDVQKAIQSLLPPDAILVGHSLEHDLQAMKMTHPFCLDVGHVLNYTNSNTEFRNSLKNLTELFLG 349

  Fly   484 EIIQENIDGHDSIEDSRATLKLVKKKLANSIEFGD-------------------QILTQHKQLQE 529
            ..||... ||.|.||:.|.::|.:.||...:.||:                   :|:|    ..|
 Worm   350 AQIQSEF-GHCSYEDAWAAMRLAQLKLEKGLMFGNVSFGWKYSEYAKNNGAVEKKIVT----AAE 409

  Fly   530 LANASSGD---------TISNNLFAHVAKRDKRTAIVTVG-------ELQPRLKEVIEKAGEAAP 578
            :.:....|         |::|.....|:...|....|.:|       ..|..|....||  :|:|
 Worm   410 ITSKPCTDCSQPTVVACTVANCRCRFVSTPSKCVHCVKIGISAQGDFHWQDTLDVDHEK--KASP 472

  Fly   579 ------KDQSTSV------HVHEVSTAKEAIRK------------VNEVA---LENALTIANL-- 614
                  ||:..||      .:.:.....:.:|.            ||.||   |.:::.:..:
 Worm   473 IGNYLKKDKMKSVMCAFDTAILDCPPISKKVRSKLHSSFPSYNGFVNSVASEMLNDSVILVEIDK 537

  Fly   615 --------RVPEQDFILDSAQRSVAKLDKTIDRLWKSVAHNGLFLVIMGGSTECSKGVAKIAIK 670
                    ...||..:.|:|:    .|::.:::|..:.|.|.|.::|:..||   |.|..:.:|
 Worm   538 EKIEPLEETDSEQGEVPDNAE----ALNRILEKLVAATAKNSLIMMILSNST---KNVLYVRVK 594

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rexo5	NP_648050.1	REX1_like	357..507	CDD:99848	77/150 (51%)
C05C8.5	NP_504838.1	REX1_like	222..372	CDD:99848	77/150 (51%)